[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. STRAIN=Hereford; TISSUE=Fetal cerebellum; NIH - Mammalian Gene Collection (MGC) project; Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: 2 glutathione + H₂O₂ = glutathione disulfide + 2 H₂O.
SUBCELLULAR LOCATION: Secreted (Potential).
SIMILARITY: Belongs to the glutathione peroxidase family.

Copyright

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Cross-references

Sequence databases

EMBL

BC148128; AAI48129.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_001094583.1; -.

UniGene

Bt.11662

3D structure databases

ModBase

A6QLY2.

Family and domain databases

InterPro

IPR013376; Glut_perox_Gpx7.
IPR000889; Glut_peroxidase.
IPR012335; Thioredoxin_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.30.10; Thioredoxin_fold; 1.

PANTHER

PTHR11592; Glut_peroxidase; 1.

Pfam

PF00255; GSHPx; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000303; Glutathion_perox; 1.

PRINTS

PR01011; GLUTPROXDASE.

TIGRFAMs

TIGR02540; gpx7; 1.

PROSITE

PS00460; GLUTATHIONE_PEROXID_1; 1.
PS00763; GLUTATHIONE_PEROXID_2; 1.
PS51355; GLUTATHIONE_PEROXID_3; 1.
PROSITE graphical view of domain structure (profiles).

BLOCKS

A6QLY2.

Genome annotation databases

Ensembl

ENSBTAG00000018281; Bos taurus. [Contig view]

GeneID

523311; -.

KEGG

bta:523311; -.

Other

ProtoNet

A6QLY2.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Oxidoreductase; Peroxidase; Secreted; Signal.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`SIGNAL`	`1 18`	`18`	`Potential.`
`CHAIN`	`19 186`	`168`	`Glutathione peroxidase 7.`	`PRO_0000317754`
`ACT_SITE`	`56 56`		`By similarity.`

Sequence information

Length: 186 AA [This is the length of the unprocessed precursor]

Molecular weight: 20908 Da [This is the MW of the unprocessed precursor]

CRC64: 6CADF950D7A02E28 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MVAARAAAWL LLAAAACAPR EQDFYDFKAV NIRGKLVSLE KYRGSVSLVV NVASECGFTD 

        70         80         90        100        110        120 
QHYRALQQLQ RDLGPHHFNV LAFPCNQFGQ QEPDSNKEIE SFARRTYSVS FPMFSKIAVT 

       130        140        150        160        170        180 
GTGAHPAFKY LTETSGKEPT WNFWKYLVAP DGKVIGAWDP TVSVEEIRPQ ITALVRKLIL 


KKREDL

A6QLY2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools