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UniProtKB/Swiss-Prot entry A5V807

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FOLD2_SPHWW
Primary accession number A5V807
Secondary accession numbers None
Integrated into Swiss-Prot on June 10, 2008
Sequence was last modified on July 10, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 17)
Name and origin of the protein
Protein name Bifunctional protein folD 2
Synonyms None
Includes Methylenetetrahydrofolate dehydrogenase
     (EC 1.5.1.5)
Methenyltetrahydrofolate cyclohydrolase
     (EC 3.5.4.9)
Gene name
Name: folD2
OrderedLocusNames: Swit_2064
From
Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) [TaxID: 392499] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; Sphingomonadaceae; Sphingomonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Halden R.U., Miller T.R., Salzberg S.L., Eisen J.A., Richardson P.;
"Complete sequence of chromosome of Sphingomonas wittichii RW1.";
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000699; ABQ68423.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001262561.1; -.
3D structure databases
ModBase A5V807.
Ontologies
GO
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0004477; Molecular function: methenyltetrahydrofolate cyclohydrolase activity (inferred from electronic annotation from HAMAP).
GO:0004488; Molecular function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (inferred from electronic annotation from HAMAP).
GO:0009396; Biological process: folic acid and derivative biosynthetic process (inferred from electronic annotation from InterPro).
GO:0000105; Biological process: histidine biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0009086; Biological process: methionine biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0006730; Biological process: one-carbon compound metabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006164; Biological process: purine nucleotide biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01576; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR000672; THF_DHase/CycOHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00763; THF_DHG_CYH; 1.
PF02882; THF_DHG_CYH_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00085; THFDHDRGNASE.
ProDom PD002300; THFDhg/Cyc_hydro; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00766; THF_DHG_CYH_1; FALSE_NEG.
PS00767; THF_DHG_CYH_2; 1.
BLOCKS A5V807.
ProtoNet A5V807.
Genome annotation databases
GeneID 5197607; -.
GenomeReviews CP000699_GR; Swit_2064.
KEGG swi:Swit_2064; -.
NMPDR fig|392499.4.peg.2303; -.
CMR A5V807; Swit_2064.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis; Hydrolase; Methionine biosynthesis; Multifunctional enzyme; NADP; One-carbon metabolism; Oxidoreductase; Purine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   297  297     Bifunctional protein folD 2. PRO_0000340600
Sequence information
Length: 297 AA [This is the length of the unprocessed precursor] Molecular weight: 30943 Da [This is the MW of the unprocessed precursor] CRC64: 08CA8ECBA19B597A [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAPSHAAHDS AATAHRIDGR AIARSLDERT AAAVRAIVAR DGAPPGLAVV LVGNDPASEV 

        70         80         90        100        110        120 
YVGRKIEACR RVGILSFEHR LPAQTTQDAL LTLIARLNAD PTIHGILVQV PLPSHIDDGM 

       130        140        150        160        170        180 
VLSAIDPAKD VDGFHPVNVG RLSTGTGGLV PCTPLGVMML LDSVIDDMKG MDAVVIGKSN 

       190        200        210        220        230        240 
IVGKPIAMLL LEREATVTVT HIETRGLPDI VRKADIIVAA AGAPRLVKGY WVKEGAVIID 

       250        260        270        280        290 
VGITRLPGEG GKTRLVGDVA FDEVQHARAV TPVPGGVGPM TIACLLANTV KAAEMRG
A5V807 in FASTA format

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