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UniProtKB/Swiss-Prot entry A4Z2G7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRD_BRASO
Primary accession number A4Z2G7
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on May 29, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 15)
Name and origin of the protein
Protein name Dihydroorotate dehydrogenase
Synonyms EC 1.3.3.1
Dihydroorotate oxidase
DHOdehase
DHODase
DHOD
Gene name
Name: pyrD
OrderedLocusNames: BRADO6742
From
Bradyrhizobium sp. (strain ORS278) [TaxID: 114615] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1139548; PubMed=17540897 [NCBI, ExPASy, EBI, Israel, Japan]
Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z., Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
"Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
Science 316:1307-1312(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU234118; CAL80343.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001208558.1; -.
3D structure databases
ModBase A4Z2G7.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from HAMAP).
GO:0004158; Molecular function: dihydroorotate oxidase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00225; -; 1.
PBIL [Tree]
InterPro IPR012135; DHO_DHase_1_2.
IPR005719; DHO_DHase_2.
IPR001295; Dihydroorotate_DHase_core.
Graphical view of domain structure.
Pfam PF01180; DHO_dh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000164; DHO_oxidase; 1.
TIGRFAMs TIGR01036; pyrD_sub2; 1.
PROSITE PS00911; DHODEHASE_1; 1.
PS00912; DHODEHASE_2; 1.
BLOCKS A4Z2G7.
Genome annotation databases
GeneID 5119338; -.
GenomeReviews CU234118_GR; BRADO6742.
KEGG bra:BRADO6742; -.
CMR A4Z2G7; BRADO6742.
Other
ProtoNet A4Z2G7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; Flavoprotein; FMN; Membrane; Oxidoreductase; Pyrimidine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   364  364     Dihydroorotate dehydrogenase. PRO_1000024156
ACT_SITE   173   173        Nucleophile (By similarity). 
Sequence information
Length: 364 AA [This is the length of the unprocessed precursor] Molecular weight: 39208 Da [This is the MW of the unprocessed precursor] CRC64: AA9B41BB22A0DF17 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MIRAFDQLSL PLLRWLDAED AHRLAIQGLK LLPAVKPRAD DAKLAVRAFG LNFPNPVGMA 

        70         80         90        100        110        120 
AGFDKNAEVP DALLRLGFGF VEIGSVTPRP QSGNPRPRLF RLERDEAVIN RMGFNNDGAE 

       130        140        150        160        170        180 
IVLRRLAGRA NQGGIVGVNV GANKDSADRV ADYVRLIETF APVASYFTVN ISSPNTPGLR 

       190        200        210        220        230        240 
NLQQASQLDD LLTKVLEARD RVRRKAGDTP VLLKIAPDLS LAELDDVVHV ARSRGVDGMI 

       250        260        270        280        290        300 
VSNTTLARPN SLREQMRAKE QGGLSGRPLF RLSTRMVAET FVRVEGAFPL IGVGGIDTGG 

       310        320        330        340        350        360 
AALTKIRAGA SLIQLYSSLV YKGLGLVESI KADLTSTLLR TGRESLSEIV GADAATITAE 


DWPV 

A4Z2G7 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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