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UniProtKB/Swiss-Prot entry A1VMA8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUAC_POLNA
Primary accession number A1VMA8
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on February 6, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 11)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: Pnap_1472
From
Polaromonas naphthalenivorans (strain CJ2) [TaxID: 365044] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Comamonadaceae; Polaromonas.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Madsen E.L., Richardson P.;
"Complete sequence of chromosome1 of Polaromonas naphthalenivorans CJ2.";
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000529; ABM36786.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_981707.1; -.
3D structure databases
ModBase A1VMA8.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
BLOCKS A1VMA8.
Genome annotation databases
GeneID 4689530; -.
GenomeReviews CP000529_GR; Pnap_1472.
KEGG pna:Pnap_1472; -.
CMR A1VMA8; Pnap_1472.
Other
ProtoNet A1VMA8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   325  325     GMP reductase. PRO_0000294281
NP_BIND   202   225  24     NADP (Potential). 
ACT_SITE   173   173        Thioimidate intermediate (By similarity). 
Sequence information
Length: 325 AA [This is the length of the unprocessed precursor] Molecular weight: 35940 Da [This is the MW of the unprocessed precursor] CRC64: F79439DE86C2F2DF [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEIFDYDNIL LLPRKCRVES RAECDASVTL GQRSFRIPVV PANMKTVVNE DICVWMAQNG 

        70         80         90        100        110        120 
YFYVMHRFDL DNLQFVRDMQ ARGVYASISL GVKQPDYDTV DRLVAEGLAP EYITIDIAHG 

       130        140        150        160        170        180 
HADTVRKMIA YLKNHLPESF VIAGNVATPE AVIDLENWGA DATKVGIGPG KVCITKMKTG 

       190        200        210        220        230        240 
FGTGGWQLSA LKWCARVATK PIIADGGIRE HGDIAKSIRF GATMVMIGSM LAGLEESPGQ 

       250        260        270        280        290        300 
TVEVDGKLFK EYYGSASDFN KGEYKHVEGK RILEPIKGKL VDTLREMEED VQSAISYAGG 

       310        320 
TRLMDIRKVN YVVLGGKNSN EDLMM 

A1VMA8 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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