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UniProtKB/Swiss-Prot entry A1KF54


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GABD1_MYCBP
Primary accession number A1KF54
Secondary accession numbers None
Integrated into Swiss-Prot on November 13, 2007
Sequence was last modified on November 13, 2007 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 12)
Name and origin of the protein
Protein name Succinate-semialdehyde dehydrogenase [NADP+] 1
Synonyms SSADH 1
SSDH 1
EC 1.2.1.16
Gene name
Name: gabD1
OrderedLocusNames: BCG_0271c
From
Mycobacterium bovis (strain BCG / Pasteur 1173P2) [TaxID: 410289] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0700869104; PubMed=17372194 [NCBI, ExPASy, EBI, Israel, Japan]
Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P., Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K., Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C., Barrell B.G., Parkhill J., Cole S.T.;
"Genome plasticity of BCG and impact on vaccine efficacy.";
Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AM408590; CAL70255.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_976369.1; -.
3D structure databases
ModBase A1KF54.
Ontologies
GO
GO:0009013; Molecular function: succinate-semialdehyde dehydrogenase [NAD(P)+] activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; FALSE_NEG.
BLOCKS A1KF54.
Genome annotation databases
GeneID 4698713; -.
GenomeReviews AM408590_GR; BCG_0271c.
KEGG mbb:BCG_0271c; -.
CMR A1KF54; BCG_0271c.
Other
ProtoNet A1KF54.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   457  457     Succinate-semialdehyde dehydrogenase [NADP+] 1. PRO_0000310702
NP_BIND   209   214  6     NAD or NADP (By similarity). 
COMPBIAS   19   117  99     Ala-rich. 
ACT_SITE   231   231        By similarity. 
ACT_SITE   265   265        By similarity. 
Sequence information
Length: 457 AA [This is the length of the unprocessed precursor] Molecular weight: 48545 Da [This is the MW of the unprocessed precursor] CRC64: B391266C5441A05F [This is a checksum on the sequence]
        10         20         30         40         50         60 
MPIATINPAT GETVKTFTAA TDDEVDAAIA RAHRRFADYR QTSFAQRARW ANATADLLEA 

        70         80         90        100        110        120 
EADQAAAMMT LEMGKTLAAA KAEALKCAKG FRYYAENAEA LLADEPADAA KVGASAAYGR 

       130        140        150        160        170        180 
YQPLGVILAV MPWNFPLWQA VRFAAPALMA GNVGLLKHAS NVPQCALYLA DVIARGGFPD 

       190        200        210        220        230        240 
GCFQTLLVSS GAVEAILRDP RVAAATLTGS EPAGQSVGAI AGNEIKPTVL ELGGSDPFIV 

       250        260        270        280        290        300 
MPSADLDAAV STAVTGRVQN NGQSCIAAKR FIVHADIYDD FVDKFVARMA ALRVGDPTDP 

       310        320        330        340        350        360 
DTDVGPLATE QGRNEVAKQV EDAAAAGAVI RCGGKRLDRP GWFYPPTVIT DISKDMALYT 

       370        380        390        400        410        420 
EEVFGPVASV FRAANIDEAV EIANATTFGL GSNAWTRDET EQRRFIDDIV AGQVFINGMT 

       430        440        450 
VSYPELPFGG VKRSGYGREL SAHGIREFCN IKTVWIA 

A1KF54 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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