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UniProtKB/Swiss-Prot entry A1CZ92


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CARA_NEOFI
Primary accession number A1CZ92
Secondary accession numbers None
Integrated into Swiss-Prot on June 12, 2007
Sequence was last modified on January 23, 2007 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 14)
Name and origin of the protein
Protein name Carbamoyl-phosphate synthase arginine-specific small chain
Synonyms CPS-A
EC 6.3.5.5
Arginine-specific carbamoyl-phosphate synthetase, glutamine chain
Gene name
Name: cpa1
ORFNames: NFIA_036340
From
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) [TaxID: 331117] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; Neosartorya.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.1000046; PubMed=18404212 [NCBI, ExPASy, EBI, Israel, Japan]
Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J., Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H., Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M., Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J., Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C., White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H., Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
"Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus.";
PLoS Genet. 4:E1000046-E1000046(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
DS027686; EAW24062.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_001265959.1; -.
3D structure databases
ModBase A1CZ92.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0004088; Molecular function: carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (inferred from electronic annotation from EC).
GO:0006526; Biological process: arginine biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR006220; Anth_synthII.
IPR001317; CarbamoylP_synth_GATase.
IPR006274; CarbamoylP_synth_ssu.
IPR002474; CarbamoylP_synth_ssu_N.
IPR011702; GATASE.
IPR012998; GATase_1_AS.
IPR000991; GATase_class1_C.
Graphical view of domain structure.
PANTHER PTHR11405:SF4; CarA_synth_small; 1.
Pfam PF00988; CPSase_sm_chain; 1.
PF00117; GATase; 1.
Pfam graphical view of domain structure.
PRINTS PR00097; ANTSNTHASEII.
PR00099; CPSGATASE.
PR00096; GATASE.
TIGRFAMs TIGR01368; CPSaseIIsmall; 1.
PROSITE PS51273; GATASE_TYPE_1; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS A1CZ92.
ProtoNet A1CZ92.
Genome annotation databases
GeneID 4592759; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome; Cytoplasm; Glutamine amidotransferase; Ligase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   453  453     Carbamoyl-phosphate synthase arginine-specific small chain. PRO_0000290597
DOMAIN   219   406  188     Glutamine amidotransferase type-1. 
COMPBIAS   443   453  11     Poly-Ala. 
ACT_SITE   295   295        Nucleophile (By similarity). 
ACT_SITE   379   379        By similarity. 
ACT_SITE   381   381        By similarity. 
Sequence information
Length: 453 AA [This is the length of the unprocessed precursor] Molecular weight: 49347 Da [This is the MW of the unprocessed precursor] CRC64: 549077BF63DB7BFF [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFARVFKAMP ARASALTSVN ASIQARFMAT VRQQRTAHER ATFTIRDGPI FHGKSFGART 

        70         80         90        100        110        120 
NISGEAVFTT SLVGYPESLT DPSYRGQILV FTQPLIGNYG VPSAERDQHG LLKYFESPNL 

       130        140        150        160        170        180 
QAAGVVVADV AEQYSHWTAV ESLGEWCARE GVPAISGVDT RAIVTYLREQ GSSLARITVG 

       190        200        210        220        230        240 
EEYDADQDEA FTDPEQIHLV RQVSTKAPFH VSAADPQCHV AVIDCGVKEN ILRSLVSRGA 

       250        260        270        280        290        300 
SITVFPFDYP IHKVAHHFDG VFISNGPGDP THCQETTYHL RRLMETSQVP IFGICLGHQL 

       310        320        330        340        350        360 
LALAAGARTI KLKYGNRAHN IPALDLSTGR CHITSQNHGY AVDASTLPSD WKPYFVNLND 

       370        380        390        400        410        420 
SSNEGMIHKS RPIFSTQFHP EAKGGPLDSS YLFDIYIDSV KKYKASQAAF HPQRDSLPSP 

       430        440        450 
LLVDLLAKER VGVQPTIGMQ NIAAAATAAA AAA 

A1CZ92 in FASTA format

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NPSA logo NPSA Sequence analysis tools

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