ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry A0KHR8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name MAO1_AERHH
Primary accession number A0KHR8
Secondary accession numbers None
Integrated into Swiss-Prot on March 18, 2008
Sequence was last modified on March 18, 2008 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 19)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: AHA_1278
From
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [TaxID: 380703] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales; Aeromonadaceae; Aeromonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.00621-06; PubMed=16980456 [NCBI, ExPASy, EBI, Israel, Japan]
Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
J. Bacteriol. 188:8272-8282(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000462; ABK38619.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_855819.1; -.
3D structure databases
ModBase A0KHR8.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS A0KHR8.
Genome annotation databases
GeneID 4490711; -.
GenomeReviews CP000462_GR; AHA_1278.
KEGG aha:AHA_1278; -.
TIGR AHA_1278; -.
Other
ProtoNet A0KHR8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   564  564     NAD-dependent malic enzyme. PRO_0000323535
ACT_SITE   104   104        Proton donor (By similarity). 
ACT_SITE   175   175        Proton acceptor (By similarity). 
METAL   246   246        Divalent metal cation (By similarity). 
METAL   247   247        Divalent metal cation (By similarity). 
METAL   270   270        Divalent metal cation (By similarity). 
BINDING   157   157        NAD (By similarity). 
BINDING   270   270        NAD (By similarity). 
BINDING   417   417        NAD (By similarity). 
SITE   270   270  1     Important for activity (By similarity). 
Sequence information
Length: 564 AA [This is the length of the unprocessed precursor] Molecular weight: 62671 Da [This is the MW of the unprocessed precursor] CRC64: 270B94F4609283F3 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MFEDNNQKRP LYIPYAGPAL LETPLLNKGS AFTSEERSNF NLEGLLPQNI ETIEEQAERA 

        70         80         90        100        110        120 
YRQFMAFGND MDKHIYLRNI QDTNETLFYR LLTNHLTEML PVIYTPTVGK ACEEFSNIYR 

       130        140        150        160        170        180 
RARGLFISYP DKDRIDDMLQ NATKQNVKVI VVTDGERILG LGDQGIGGMG IPIGKLSLYT 

       190        200        210        220        230        240 
ACGGISPAYC LPVVLDVGTN NQQLLNDPFY MGWRNPRISG EEYAEFVDAF IQAVKRRWPD 

       250        260        270        280        290        300 
ILLQFEDFAQ NNAMPLLNRY KNELCCFNDD IQGTAAVTLG SLIAACKASG AKLSEKRVAF 

       310        320        330        340        350        360 
LGAGSAGCGI AEQIVAQMKA EGLTDAQARS RVFMVDRFGL ITDKIPNQLD FQRRLSQPVE 

       370        380        390        400        410        420 
RIADWPVGDN ISLLEVMEHG RPDILIGVSG QPGLFTEEVV KTMHKHCARP IIFPLSNPTS 

       430        440        450        460        470        480 
RVEATPADLI RWTDGQALVA TGSPFAPVEY KGKRYVIAQC NNSFIFPGIG LGVIAAGATR 

       490        500        510        520        530        540 
VTDAMLMSAS RALAECSPLV KGEEGSLLPD LADIHQVSRY IAKMVAKTAM LQGKAVQTPD 

       550        560 
EVIDQSIEAN FWRPEYRRYR RTSF
A0KHR8 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!