Swiss Institute of Bioinformatics

---

The UniProt Knowledgebase consists of:

• UniProtKB/Swiss-Prot; a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases [More details / References / Linking to UniProtKB/Swiss-Prot / User manual / Recent changes / Disclaimer].
• UniProtKB/TrEMBL; a computer-annotated supplement of Swiss-Prot that contains all the translations of EMBL nucleotide sequence entries not yet integrated in Swiss-Prot.

These databases are developed by the Swiss-Prot groups at SIB and at EBI.

UniProt Knowledgebase Release 15.7 consists of: UniProtKB/Swiss-Prot Release 57.13 of 19-Jan-10: 514212 entries (More statistics) UniProtKB/TrEMBL Release 40.13 of 19-Jan-10: 10158056 entries (More statistics)

> Swiss-Prot headlines XMRV complete proteome in UniProtKB/Swiss-Prot (Read more...)

---

Access to the UniProt Knowledgebase
UniProt web site UniProtKB Taxonomy browser ViralZone - Portal to viral UniProtKB/Swiss-Prot entries BLAST similarity search Retrieve a list of UniProtKB entries Randomly retrieve a UniProtKB entry UniProtKB Sequence/Annotation Version Database

Documents and services

Swiss-Prot documents - user manual, release notes, indices and lots of other important documents and lists Swiss-Shop - a service that allows you to automatically obtain (by email) new UniProtKB/Swiss-Prot sequence entries relevant to your field(s) of interest Updates and submissions FTP: Obtain a local copy of the UniProt Knowledgebase UniProt Knowledgebase on DVD: Users may subscribe to the Swiss-Prot/TrEMBL CDs which are produced at each major release of the database. Please contact specifying a request for it. Human proteomics initiative (HPI) High-quality Automated and Manual Annotation of microbial Proteomes (HAMAP) Plant Proteome Annotation Project (PPAP) Toxin Annotation Project (Tox-Prot) Protein Spotlight Protéines à la «Une» Links to gene/protein specific databases and resources Links to post-translational modifications databases and resources Swissknife - a tool to parse Swiss-Prot In-Silico Analysis of Proteins Celebrating the 20th anniversary of Swiss-Prot Swiss-Prot funding crisis of 1996

---

Last modified 20/Jan/2010 by ELG