Species code:	HAES1
Taxonomy:	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Histophilus (TaxID: 205914) [NEWT/ NCBI]
Description:	Haemophilus somnus is the cause of a variety of systemic diseases in cattle, including thrombotic-meningoencephalitis, pneumonia, abortion and other reproductive diseases, arthritis, myocarditis, and septicemia. Diseases due to H. somnus account for millions of dollars in losses to the cattle industry, and are particularly prevalent in feedlots; additionally this agent may also affect dairy cattle. It may be the most economically important pathogen of feedlot cattle. H.somnus 129Pt is an avirulent commensal strain. Extensive comparisons between 3 available Haemophilus were performed (H.somnus 129Pt, H.influenzae Rd and H.ducreyi 35000HP). It encodes the shikimate pathway for chorismate biosynthesis and all components of the ubiquinone and menaquinone synthesis pathways, as well as genes involved in lipooligosaccharide biosynthesis, carbohydrate uptake and metabolism, cation transport, amino acid metabolism and so on, that may be important to its ecological niche.
Properties:	Presence of flagella: No Interaction: Animal commensal in Mammalia; Animal pathogen in Mammalia; Avirulent strain Number of membranes: 2 Number of inteins:0
Statistics:	Number of HAES1 entries in the UniProt Knowledgebase: 1793 (366 in UniProtKB/Swiss-Prot + 1427 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number CP000436 (circular; 2,007,700 bp) (download entry) (download Genome Reviews). • Plasmid pHS129 EMBL accession number CP000019 (circular; 5,178 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=17172329; [ NCBI , EBI , Israel , Japan ] Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O., Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N., Xie G., Inzana T.J. ; "Complete genome sequence of Haemophilus somnus (Histophilus somni) strain 129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus influenzae Rd."; J. Bacteriol. 189:1890-1898(2007).
Web links:	Official genome site(s): http://genome.jgi-psf.org/finished_microbes/haeso/haeso.home.html Other web sites: Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid205914%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Hsom_129PT NMPDR: http://www.nmpdr.org/FIG/wiki/rest.cgi/NmpdrPlugin/SeedViewer?pattern=205914.1;page=SearchResult PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p322_Hae_somnu  EBI Proteome Analysis page

• Genome Proximity Viewer: This program displays the genes that are found in the genomic environment of a selected locus.
  
  
• Perform a BLAST search against all proteins from this proteome
  
  
• Download a file by FTP containing all UniProt Knowledgebase entries of this proteome
  • in UniProt Knowledgebase format
  • in FASTA format
  
  
• Retrieve set of characterized or identified proteins for this proteome
  
  
• Retrieve set of proteins with 3D structure for this proteome