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HAMAP: Escherichia coli O6:K15:H31 (strain 536 / UPEC) complete proteome

General information

Species:  Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Species code: ECOL5
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia (TaxID: 362663) [NEWT/ NCBI]
Description: Escherichia coli is a Gram-negative straight rod, which either uses peritrichous flagella for mobility or is nonmotile. It is a facultatively anaerobic chemoorganotroph capable of both respiratory and fermentative metabolism. E.coli serves a useful function in the body by suppressing the growth of harmful bacterial species and by synthesising appreciable amounts of vitamins. It is an important component of the biosphere. It colonizes the lower gut of animals and survives when released to the natural environment, allowing widespread dissemination to new hosts. Pathogenic E.coli strains are responsible for infection of the enteric, urinary, pulmonary and nervous systems. The uropathogenic Escherichia coli (UPEC) strain 536 was originally isolated from a patient with acute pyelonephritis. The strain 536 (O6:K15:H31) is one of the model organisms of extraintestinal E. coli. The genome consists of a circular chromosome of 4.9 Mbp, and harbors 5 well characterized pathogenicity islands and a newly identified sixth island, encoding the key virulence factors of this strain. Excision of 4 of the 6 islands was observed.
Properties: Presence of flagella: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of ECOL5 entries in the UniProt Knowledgebase: 4605 (825 in UniProtKB/Swiss-Prot + 3780 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    536 / UPEC
Genome structure:
Chromosome EMBL accession number CP000247 (circular; 4,938,920 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] PubMed=16879640; [ NCBI , EBI , Israel , Japan ]
Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U., Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J. ;
"Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536.";
Mol. Microbiol. 61:584-595(2006).
Web links:
Official genome site(s):
http://www.g2l.bio.uni-goettingen.de/projects/f_projects.html
Other web sites:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Escherichia&GLspecies=coli&GLsupStrain=536
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid362663%5Borgn%5D
ERIC: http://www.ericbrc.org/portal/eric/ecoliupec536
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Ecol_536
PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p16235_Esc_coli
 EBI Proteome Analysis page



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