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HAMAP: Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) complete proteome

General information

Species:  Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
Species code: CLOP1
Taxonomy: Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium (TaxID: 195103) [NEWT/ NCBI]
Description: Rod-shaped Gram-positive bacterium that is anaerobic and spore forming. It is widely distributed in the environment and frequently occurs in the intestines of humans and many domestic and feral animals. Spores of the organism persist in soil, sediments, and areas subject to human or animal fecal pollution. The common form of perfringens food poisoning is characterized by intense abdominal cramps and diarrhea which begin 8-22 hours after consumption of foods containing large numbers of those bacteria capable of producing the food poisoning enterotoxin. Type A strains can also cause wound contamination, traumatic or nontraumatic myonecrosis (gas gangrene), clostridial cellulitis, intra-abdominal sepsis and gangrenous cholecystitis. ATCC 13124 (a type A strain gas gangrene isolate) is the species type strain, does not produce the C.perfringens enterotoxin responsible for food poisoning and is considerably more virulent than strain 13 in animal gangrene models.
Properties: Presence of flagella: not known
Interaction: Animal commensal in Mammalia; Animal pathogen in Mammalia
Number of membranes: 1
Number of inteins:0
Statistics: Number of CLOP1 entries in the UniProt Knowledgebase: 2873 (328 in UniProtKB/Swiss-Prot + 2545 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    ATCC 13124 / NCTC 8237
Genome structure:
Chromosome EMBL accession number CP000246 (circular; 3,256,683 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] PubMed=16825665; [ NCBI , EBI , Israel , Japan ]
Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B., Paulsen I.T. ;
"Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens.";
Genome Res. 16:1031-1040(2006).
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid195103%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Cper_ATCC13124
Pathema: http://pathema.jcvi.org/tigr-scripts/Clostridium/shared/GenomePage.cgi?org=bcl
PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p304_Clo_perfr
 EBI Proteome Analysis page



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