Species code:	CHRSD
Taxonomy:	Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales; Halomonadaceae; Chromohalobacter (TaxID: 290398) [NEWT/ NCBI]
Description:	Chromohalobacter salexigens DSM 3043 is a metabolically versatile, moderately halophilic and halotolerant bacterium, isolated from a solar saltern on Bonaire, Netherlands Antilles. It is a gamma-Proteobacterium, and as such, closely related to Pseudomonas and Eschrichia coli . It has resistance functions to heavy metals and can degrade aromatic hydrocarbons. It is an aerobic chemoorganotroph that grows on a wide range of simple carbon compounds at NaCl concentrations between 0.5 M and 4 M, with an optimum at 2–2.5 M. Some groups of bacteria balance the high osmolality of their environment with high intracellular concentrations of KCl. Instead C. salexigens uses organic solutes to provide the necessary osmotic balance. These organic ‘compatible’ solutes, such as glycine betaine, ectoine, simple sugars, and many others are much less disruptive to normal functioning of enzymes than high concentrations of KCl, and accordingly less farreaching adaptations are required in the protein structure. Osmoadaptation is achieved by de novo synthesis of ectoine (ectABC) and hydroxyectoine, and by the uptake of osmoprotectants such as choline, choline-O-sulfate and glycine betaine.
Properties:	Presence of flagella: Yes Interaction: No Number of membranes: 2 Number of inteins:0
Statistics:	Number of CHRSD entries in the UniProt Knowledgebase: 3298 (353 in UniProtKB/Swiss-Prot + 2945 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number CP000285 (circular; 3,696,649 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N., O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R., Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D., Canovas D., Richardson P. ; "Complete sequence of Chromohalobacter salexigens DSM 3043."; Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
Web links:	Official genome site(s): http://genome.jgi-psf.org/finished_microbes/chrsa/chrsa.home.html Other web sites: CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Chromohalobacter&GLspecies=salexigens&GLsupStrain=DSM3043 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid290398%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Csal_DSM3043 PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p12636_Chr_salex  EBI Proteome Analysis page

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