Species code:	BURMA
Taxonomy:	Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia (TaxID: 13373) [NEWT/ NCBI]
Description:	Burkholderia mallei is the etiologic agent of glanders, a disease that is often fatal. Its natural reservoir are horses and other equines, but it can be occasionally transmitted to humans either by inhalation or through breaks in the skin. It is an obligate animal pathogen, with an intracellular localization. B. mallei is highly infectious as an aerosol and was used as a biological weapon in the American Civil War and in both World Wars. Unlike the related bacterium B.pseudomallei it is non-motile. One of its virulence factors has been identified as the type III secretion system, another as the newly characterized type VI (T6S).
Properties:	Presence of flagella: No Interaction: Animal pathogen in Mammalia (intracellular obligate) Number of membranes: 2 Number of inteins:0
Statistics:	Number of BURMA entries in the UniProt Knowledgebase: 4797 (434 in UniProtKB/Swiss-Prot + 4363 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome 1 EMBL accession number CP000010 (circular; 3,510,148 bp) (download entry) (download Genome Reviews). • Chromosome 2 EMBL accession number CP000011 (circular; 2,325,379 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=15377793; [ NCBI , EBI , Israel , Japan ] Nierman W.C., DeShazer D., Kim H.S., Tettelin H., Nelson K.E., Feldblyum T.V., Ulrich R.L., Ronning C.M., Brinkac L.M., Daugherty S.C., Davidsen T.D., DeBoy R.T., Dimitrov G., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Khouri H.M., Kolonay J.F., Madupu R., Mohammoud Y., Nelson W.C., Radune D., Romero C.M., Sarria S., Selengut J., Shamblin C., Sullivan S.A., White O., Yu Y., Zafar N., Zhou L., Fraser C.M. ; "Structural flexibility in the Burkholderia mallei genome."; Proc. Natl. Acad. Sci. U.S.A. 101:14246-14251(2004).
Web links:	Official genome site(s): http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=gbm Other web sites: CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Burkholderia&GLspecies=mallei&GLstrain=ATCC23344 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid243160%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Bmal_ATCC23344 Pathema: http://pathema.tigr.org/tigr-scripts/Burkholderia/GenomePage.cgi?org=gbm PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p171_Bur_malle  EBI Proteome Analysis page

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