Species code:	BORA1
Taxonomy:	Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella (TaxID: 360910) [NEWT/ NCBI]
Description:	Bordetella avium is a Gram-negative aerobic bacterium that causes bordetellosis in birds. Bordetella avium (strain 197N) is a spontaneous nalidixic acid-resistant derivative of virulent strain 197. Bordetella avium (strain 197N) was isolated from a diseased turkey in a commercial flock in the early 1980's. It was commonly thought to infect mostly commercially grown turkeys but it is also found in a variety of healthy wild and domesticated birds. Bordetellosis is highly contagious producing an upper respiratory tract infection that most often leads to death in chicks. The bacterium is easily transmitted by aerosols, leading to a rapid spread of the disease in facilities where birds are housed closely together. With 3417 predicted coding sequences, B.avium (strain 197N) has the smallest genome and gene complement of the sequenced bordetellae. Over 1100 genes present in B.avium but not in B.bronchiseptica were identified. It includes a unique fimbrial gene cluster, two hemagglutinins and their cognate secretion accessory proteins, a type II secretion system, an LPS biosynthesis locus, two separate loci potentially involved in the biosynthesis of an LPS O antigen, an operon that seems to encode enzymes for the synthesis of a cellulose-like polysaccharide and three prophages. There are 68 pseudogenes in B.avium. Bordetella avium appears to have a complete and intact set of motility and chemotaxis genes. Motility appears to be completely shut off above 40 degrees Celsius, which is close to the body temperatures of turkeys.
Properties:	Presence of flagella: Yes Interaction: Animal pathogen in Aves Number of membranes: 2 Number of inteins:0
Statistics:	Number of BORA1 entries in the UniProt Knowledgebase: 3372 (336 in UniProtKB/Swiss-Prot + 3036 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number AM167904 (circular; 3,732,255 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=16885469; [ NCBI , EBI , Israel , Japan ] Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. ; "Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction."; J. Bacteriol. 188:6002-6015(2006).
Web links:	Official genome site(s): http://www.sanger.ac.uk/Projects/B_avium/ Other web sites: Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid360910%5Borgn%5D Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Bordetella_avium.html PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p27_Bor_avium  EBI Proteome Analysis page

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