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Pierre-Alain
Binz
| Phone: email: Date of birth: |
+41-(22) 702 99 00 (prof. at GeneBio) +41-(22) 379 50 50 (prof. at SIB) +41-(22) 702 99 99 (fax) 1st August 1968 |
| - 2/1997 | PhD in bio-inorganic analytics and bioinformatics, Institute of Biochemistry, University of Zürich. |
| - 12/1991 | Diplom in chemistry, Dissertations in physical chemistry and in organic chemistry, University of Fribourg. |
| - 6/1987 | Scientific maturity, Collège St-Michel, Fribourg. |
Positions
| - since 4/2004 | Product manager and senior scientist, Geneva Bioinformatics SA (GeneBio) |
| - since 4/2000 | Maitre-Assistant and Senior Scientist
at the Swiss Institute
of Bioinformatics
(SIB), Proteome Informatics Group
(PIG), Geneva. - Budget management and scientific coordination in EU- and swiss-funded projects, - Scientific coordination with academic and commercial collaborating institutions, - Co-supervision of PhD theses and software developers, - Design and development in proteomics bioinformatics tools and databases, - Teaching in bioinformatics and proteomics, - Organisation of courses and workshops. |
| - 1998-2004 | Consultant for Geneva Bioinformatics
SA (GeneBio); - Scientific advisory activities - Instructor in the PROXEMIS proteomics-oriented bioinformatics training course. |
| - 4/2000-12/2002 | Consultant for GeneProt Inc;
participation in: - The design of proteomics experimental workflows, - In the design and set-up of a Laboratory Information Management System, - The protein identification environment. |
| - 11/1997-3/2000 | Senior scientist at the proteomics R&D group of the Laboratoire Central de Chimie Clinique, Hopital Cantonal Universitaire de Genève; responsibility of the proteomics MS facility and development of proteome informatics tools. |
| - 2/1997-10/1997 | Post-doc at the Institute of Biochemistry of the University of Zürich in biomolecular spectroscopy (RMN, MS, CD). |
| - 1994-1995 | Scientific translations for Bortolomeazzi Partner AG, Cham (ZG). |
| - 1989-1991 | -Teacher in Chemistry, Mathematics and
Phisics ate the
College of Gambach
and College St-Michel, Fribourg - Examinator for mathematics at maturity exams, College of Gambach, Fribourg (1991) |
Specific projects direction and coordination
| - 1989-1991 | Teaching in chemistry, physics and mathematics at the Colleges of Gambach and St-Michel, Fribourg |
| - 6/1991 | Examinator for mathematics at the maturity exams, College of Gambach |
| - 5/1994 | Participation at the FEBS-ESF Advanced Course: Chemistry of Metals in Biological Systems, Louvain-La-Neuve, Belgium |
| - 1994-1995 | Scientific translations for Bortolomeazzi Partner AG, Cham (ZG) |
| - 1995 | Co-supervision in the design of a OO protein database project in collaboration with the group of Prof. K.R. Dittrich in the Database Technology Group at the Institute for Informatics of the University of Zürich |
| - 6/1992-10/1997 | Teaching of practical courses for students in biochemistry and in medicine at the University of Zürich |
| - 2/1997-10/1997 | Post-doc position at the Institute of Biochemistry of the University of Zürich |
| - Since 11/1997 | Senior scientist at the Laboratoire Central de Chimie Clinique, Hopital Cantonal Universitaire de Genève and at the Swiss Institute of Bioinformatics (@ Département de Biochimie Médicale, Centre Médical Universitaire, Genève) |
| - 1999 | Teaching in the optional bioinformatics course at the Informatics Department of the University of Geneva |
| - Since 3/1999 | Reviewing activities for books and scientific articles |
| - 1999-2004 | Coordination of activities of the SIB and the Geneva University Hospital in european projects. 1) ESF Scientific Programme on "Integrated Approaches for Functional Genomics"; 2) EU Thematic Network of the Fifth Framework Program named "Comparative analysis of proteome modulation in human pathogenic bacteria for the identification of new vaccines, diagnostics and antibacterial drug targets, EBP" |
| - Since 2001 | Teaching at the GeneBio training course PROXEMIS in proteomics and bioinformatics |
| - Since 2004 |
- Project management of Phenyx,
a software dedicated to protein identifcation and characterization from
mass spectrometry data developed at GeneBio
SA - Scientific guidance in other projects such as MSight, Aldente standalone, SmileMS |
| - Since 2004 | Coordination of activities of GeneBio in european projects: 1) STREP project "LOCCANDIA" 2) Coordination action ProDaC |
Teaching
| - 04/2008 | Teaching at the Master for Proteomics and Bioinformatics, Unibersity Geneva - SIB, Geneva |
| - 01/2008 | Instructor at EMBnet course Proteomics using bioinformatics tools, Basle |
| - 10/2007 | Educational day 6th HUPO World Congress 2007, Seoul (KR) |
| - 07/2007 | EMBO Shotgun Proteomics course, York (GB) |
| - 06/2007 | Instructor at the CNRS/INRA/INSERM Atelier "Protéomique quantitative", La Gande Motte (France) |
| - 09/2006 | Instructor at the EMBO course "Bioinformatics for Mass spectrometry in Proteomics", Les Diablerets |
| - 11/2005 | Conférencier at the INRA "Ecole-Chercheurs Protéomique: Apports théoriques et pratiques en électophorèse et spectrométrie de masse", La Rochelle (France) |
| - 06/2005 | Instructor at the INSERM/INRA/CNRS Atelier phosphoprotéome, Cap d’Agde (France) |
| - 2003-2004 | Proteomics course in Separation Science, organised by the Biomedical Proteomics Research Center, Geneva and the Protein Analysis Facility, Lausanne |
| - 12/2002 | Short course in proteomics at the Swiss Proteomics Society 2002 congress, Lausanne |
| - 08/2002 | Summer course Avances en proteomica: introduccion a la bioinformatica en proteomica, El Escorial (Spain) |
| - 09/2001 | Summer course "New technologies in biomedicine". El Escorial (Spain) |
| - 08/2001 | Instructor at the EMBO course Advanced bioinformatic techniques in genomics, transcriptomics and proteomics in Uppsala (Sweden) |
| - 02/2001 | Winter Student School on Current Trends in Physicochemical Biology, Moscow |
| - 2001-2004 | Participation at the DEA in bioinformatics, Swiss Institute of Bioinformatics |
| - Since 2001 | Participation at the Medical Genetics Module of the PhD program "Molecular and Cellular biology” at the Faculty of Medicine of the University of Geneva |
| - Since 2001 | GeneBio (Geneva Bioinformatics SA, Geneva) PROXEMIS training course in proteomics and bioinformatics |
| - 5/2000 | Instructor at the Atelier de formation INSERM n°115 on Le protéome: nouvelles approches expérimentales et systèmes étudiés, Jouy-en-Josas (France) |
| - 1999 | Optional bioinformatics course at the Informatics Department of the University of Geneva |
| - 1997-2002 | participation at training courses (3 to 4 times per year) on two-dimensional polyacrylamide gel electrophoresis organized by Prof. Denis F. Hochstrasser of the Clinical Chemistry Department of the Geneva University Hospital. |
| - 6/1992-10/1997 | Practical courses for students in biochemistry and in medicine at the University of Zürich |
| - 6/1991 | Examinator for mathematics at the maturity exams, College of Gambach |
| - 1989-1991 | Chemistry, physics and mathematics at the Colleges of Gambach and St-Michel, Fribourg |
Organisation of courses and workshops
- Introduction to Mass Spectrometry. Pre-congress workshop of MedLab2000, World Trade Center, Zürich, 25th October 2000. Organized by the Mass Spectrometry Scientific Group of the SSCC/SGKC (Swiss Society of Clinical Chemistry).
- ESF Workshop Data integration in functional genomics and proteomics" (ESF site). Swiss Institute of Bioinformatics, Geneva (CH), Oct. 15-17th, 2001. Financed by the European Science Fundation (ESF) program entitled "Functional genomics", the workshop is organized by Pierre-Alain Binz (SIB), Antoine de Daruvar and Peter Rice (LION bioscience). See the meeting report at the ESF website. See also the full text version of the report published in Comparative and Functional Genomics HTML, pdf.
- Introduction course: Mass Spectrometry in Clinical Chemistry. During the General Assembly Congress of the SGKC/SSCC. ETH-Zentrum, Zürich, 9th October 2002. Organized by the Mass Spectrometry Scientific Group of the SGKC/SSCC (Swiss Society of Clinical Chemistry).
- Proteomics application exercise. organised for the Swiss Proteomics Society 2002 congress: Applied Proteomics, Lausanne (CH), Dec. 3-5 2002.
- ESF Workshop Data integration in functional genomics and
proteomics:
application to biological pathways (ESF
site), Geneva (CH), Sept. 22-24th, 2003. Financed by the European
Science
Fundation (ESF) program entitled "Functional
genomics", the workshop is organized by Pierre-Alain Binz (SIB),
Paul
van der Vet (University of Twente, NL) and Henning Hermjakob, (EBI,
UK).
- HUPO PSI 2005 Spring meeting in Siena (I), April 17-20 , 2005. Organised by the HUPO Proteomics Standards Initiative (part of the organising committee).
- ESF Workshop "Sustainability and Governance of Web and GRID Resources in Functional Genomics", Fraunhofer Institute SCAI, Schloß Birlinghoven, Sankt Augustin (D), May 9-11, 2005. (website at SCAI, at ESF program website) Financed by the European Science Fundation (ESF) program entitled "Functional genomics", the workshop is organized by Paul van der Vet (University of Twente, NL), Pierre-Alain Binz (SIB/GeneBio), Martin Hofmann (SCAI, Frauenhofer Institute, D), Theo Huibers (University of Twente, NL).| - Since 2007 | Member of the HUPO education committee |
| - Since 2006 | Member of the external advisory board of the spanish national
institute of proteomics ProteoRed
|
| - Since 2006 |
Co-chair of the HUPO PSI-MS working group (PSI). |
| - Since 2006 |
Member of the scientific committee of SwissMedLab2008 |
| - Since 2006 |
Member of the committee of the Swiss Society of Clinical
Chemistry (SSCC/SGKC) |
| - 9/2005 - 3/2006 |
Founding Member of HUPO International |
| - Since 2005 |
Member of the editorial board of the
journal Proteomics |
| - Since 2002 | Editor Proteomics of the Nature Encyclopaedia of Human Genome (Nature EHG). |
| - Since 2002 | Member of the Proteomics Standards Initiative, sub-groups mass spectrometry, mass spectrometry informatics and modifications (PSI). |
| - 2002-2003 | Member of scientific committee of the ESF Functional Genomics and Disease conference, Prague, May 14-17, 2003. |
| - Since 2001 | Member of the steering committee of the proteomics facility platform of the Lausanne University (PAF). |
| - Since 2001 | Member of the Swiss Proteomics Society (SPS). |
| - Since 5/1999 | Member of the scientific committee of the Swiss Clinical Chemistry Society (SGKC/SSCC); Chairman of the Mass Spectrometry working group. |
| - Since 1998 | Member of the Swiss Electrophoresis Society (CHEL). |
| - 1994-1998 | Member of the Union of the Swiss Societies for Experimental Biology (USGEB). |
Management, teaching, knowledge sharing
Bioinformatics
Analytics
| Languages | native french, fluent written and spoken english, fluent german and swiss-german, |
| Military grade | fourrier (02-05/1992) now retired |
Publications
-P1: Binz P.-A., Neier R. Synthèse du époxy-2 oxo-2 pentanoate de méthyle, analogue à l'acide d-amino lévulinique, précurseur biosynthétique des tétrapyrroles cycliques, Diplom thesis, University of Fribourg, CH, 1991
-P2: Binz P.-A., Bally T., Haselbach E. Contribution à la détermination de coefficients d'absorption de cations radicalaires issus de molécules aromatiques, en phase consensée, Diplom thesis, University of Fribourg, CH, 1991
-P3: Binz P.-A., Kägi J.H.R. Metallothioneins: Studies on molecular evolution and on the structural and chiroptical features of their metal thiolate clusters, PhD thesis, University of Zürich, 1997
-P4: Binz P.-A., Kägi J.H.R. Molecular evolution of vertebrate metallothioneins derived from their amino acid sequences and constitutive portions of their genes (submitted)
-P5: Binz P.-A., Zerbe O., Brouwer M., Kägi J.H.R. Spectroscopic characterisation of the two Cd3-S9 clusters in the blue crab MT-I (in preparation)
-P6: Bogumil, R., Faller, P., Binz, P.-A., Vasák, M., Charnock, J.M., Garner, C.D. Structural characterization of Cu(I) and Zn(II) sites in neuronal-growth- inhibitory factor by extended X-ray absorption fine structure (EXAFS). (1998), Eur. J. Biochem. 255, 172-7. (PMID 9692916)
-P7: Kojima, Y., Binz, P.-A., Kägi, J.H.R. Nomenclature of Metallothionein: Proposal for a revision. (1999) In: Metallothionein IV, C. Klaassen (ed.), Birkhäuser Verlag Basel, 3-6 (ISBN 3-7643-5830-0 at Birkhäuser)
-P8: Binz, P.-A., Kägi, J.H.R. Metallothionein: Molecular evolution and classification. (1999) In: Metallothionein IV, C. Klaassen (ed.), Birkhäuser Verlag Basel, 7-13 (ISBN 3-7643-5830-0 at Birkhäuser)
-P9: Binz P.-A., Wilkins M.R., Gasteiger E., Bairoch A., Appel R.D., Hochstrasser D.F. Internet Resources for Protein Identification and Characterization. (1999) In: Microcharacterization of Proteins, R. Kellner, F. Lottspeich, H.E. Meyer (Eds), Wiley-VCH, 2nd ed., 277-300 (ISBN 3-527-30084-8 at Wiley-VCH)
-P10: Yan J.X., Sanchez J.-C., Binz P.-A., Williams K.L., Hochstrasser D.F. Method for identification and quantitative analysis of proteon lysine methylation using Matrix Assised Laser Desorption Ionisation - Time of Flight Mass Spectrometry and Amino Acid Analysis (1999) Electrophoresis 20, 749-754 (PMID 10344244)
-P11: Wilkins M.R., Gasteiger E., Gooley A.A., Herbert B.R., Molloy M.P., Binz P.-A., Ou K., Sanchez J.-C., Bairoch A., Williams K.L., Hochstrasser D.F. High-throughput Mass Spectrometric Discovery of Protein Post-translational Modifications (1999) J. Mol. Biol. 289(3), 645-657 (PMID 10356335)
-P12: Binz P.-A., Müller M., Walther D., Bienvenut W.V., Gras R., Hoogland C., Bouchet G., Gasteiger E., Fabbretti R., Gay S., Palagi P, Wilkins M.R., Rouge V, Tonella L., Paesano S., Rossellat G., Karmime A., Bairoch A., Sanchez J.-C., Appel R.D., Hochstrasser D.F. A Molecular Scanner to Highly Automate Proteomic Research and to Display Proteome Images.(1999) Anal. Chem. 71, 4981-4988 (PMID 10565287)
-P13: Bienvenut W.V., Sanchez J.-C., Karmime A., Rouge V., Rose K., Binz P.-A., Hochstrasser D.F. Toward a Clinical Molecular Scanner for Proteome Research: Parallel Protein Chemical Processing Before and During Westernblot (1999) Anal. Chem. 71, 4800-4807 (PMID 10565271)
-P14: Gras R., Müller M., Gasteiger E., Gay S., Binz P.A., Bienvenut W., Hoogland C., Sanchez J.-C., Bairoch A., Hochstrasser D.F., Appel R. Improving Protein Identification from Peptide Mass Fingerprinting through a Parametrized Multi-level Scoring Algorithm and an Optimized Peak Detection. (1999) Electrophoresis 20, 3535-3550 (PMID 10612280)
-P15: S. Gay, P.-A. Binz, D.F. Hochstrasser, R.D. Appel. Modeling peptide mass fingerprinting data using the atomic composition of peptides. (1999) Electrophoresis 20, 3527-3534 (PMID 10612279)
-P16: C. Hoogland, J.-C. Sanchez, L. Tonella, P.-A. Binz, A. Bairoch, D.F. Hochstrasser, R.D. Appel The 1999 SWISS-2DPAGE database update. (2000) Nucl. Acids Res. 28, 286-288 (PMID 10592248)
-P17: Sarto C., Binz P.-A., Mocarelli P. Heat shock proteins in human cancer. (2000) Electrophoresis 21, 1218-1226 (PMID 10786894)
-P18: Hochstrasser D.F., Sanchez J.C., Binz P.A., Bienvenut W., Appel R.D. A clinical molecular scanner to study human proteome complexity. (2000) Novartis Found Symp 229:33-8; discussion 38-40 (PMID 11084927)
-P19: Gras R., Gasteiger E., Binz P.-A., Mueller M., Chopard B., Appel R.D. Classification automatique par algorithme génétique dans le cadre de l'identification par empreinte de masse peptidique. Journées Fouille dans les données par la méthode d'analyse statistique implicative, Caen, 2000, pp 59-84
-P20: Binz P.-A., Gasteiger E., Sanchez J.-C., Bairoch A., Hochstrasser D.F., Appel R.D. Proteome Analysis. In: Bioinformatics - from Genomes to Dugs, Vol.II: Applications, Th. Lengauer (Ed.), Wiley-VCH, 2001, pp69-118 (ISBN 3-527-29988-2 at Wiley-VCH)
-P21: Tonella L., Hoogland C., Binz P.-A., Appel R.D., Hochstrasser D.F., Sanchez J.-C. New perspectives in the E.coli proteome investigation (2001) Proteomics 1(3), 409-423 (PMID 11680886)
-P22: Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F. The mouse SWISS-2DPAGE database: an essential tool for proteomicS study of diabetes and obesity (2001) Proteomics 1, 136-163 (PMID 11680894)
-P23: Bienvenut W.V., Müller M., Palagi P.M., Gasteiger E., Heller M., Jung E., Giron M., Gras R., Gay S., Binz P.-A., Hugues G.J., Sanchez J.-C., Appel R.D., Hochstrasser D.F. Proteomics and Mass Spectrometry: Some aspects and recent developments. In Mass Spectrometry and genomic analysis, J.N. Houby Ed., Kluwer Academic Publishers The Netherland, 2001; pp. 1-53 (ISBN 0-7923-7173-9 at Kluver Academics Publishers)
-P24: Binz P.-A., Martin A., Taussig M., de Daruvar A. Conference Report. The ESF Programme on Integrated Approaches for Functional Genomics. Workshop on "Data Integration in Functional Genomics and Proteomics" (2002) Comparative and Functional Genomics 3, 16-21 ( Abstract, full text HTML, pdf)
-P25: C. Pellegrini, P.-A. Binz. Drug Discovery: New Horizons in Life and Biomedical Sciences (2001) Eur. Pharm. Rev. 4, 11-14
-P26: R. Stöcklin, P.-A. Binz. Challenges in Mass Spectrometry: Report of the round table discussion. Proteomics 2, 825-827 (2002) (PMID 12124927)
-P27: S. Gay, P.-A. Binz, D.F. Hochstrasser, R.D. Appel. Peptide mass fingerprinting peak intensity prediction: Extracting knowledge from spectra. Proteomics 2, 1374-1391 (2002) (PMID 12422355)
-P28: Müller M., Gras R., Binz P.-A., Hochstrasser D., Appel R.D. Molecular Scanner Experiment with Human Plasma: Improving Protein Identification by Using Intensity Distributions of Matching Peptide Masses. Proteomics 2, 1413-1425 (2002) (PMID 12422358)
-P29: G.L. Corthals, C. Pasquarello, A. Scherl, J. Burgess, L. Allard, J. Deshusses, N. Walter, S. Paesano, O. Carrette, W. Bienvenut, C. Hoogland, P.-A. Binz, M. Müller, R.D. Appel, D.F. Hochstrasser, J.-C. Sanchez. Tools and technologies in proteome analysis. in Proc. Swiss Proteomics Society 2002 Congress, Applied Proteomics, Lausanne, 3-5 December 2002, ed. Fontis Media (ISBN 2-88476-003-2), (2002), pp 9-10
-P30: M. Tuloup, C. Hoogland, P.-A. Binz, R.D. Appel. A new Peptide Mass Fingerprinting tool on ExPASy : ALDentE. in Proc. Swiss Proteomics Society 2002 Congress, Applied Proteomics, Lausanne, 3-5 December 2002, ed. Fontis Media (ISBN 2-88476-003-2), (2002), pp 93-96
-P31: K. Mostaguir, C. Hoogland, P.-A. Binz, R.D. Appel. The Make 2D-DB II Package - Conversion of federated 2-DE gel databases into a relational format and interconnection of distributed databases. in Proc. Swiss Proteomics Society 2002 Congress, Applied Proteomics, Lausanne, 3-5 December 2002, ed. Fontis Media (ISBN 2-88476-003-2), (2002), pp 73-74
-P32: K. Mostaguir, C. Hoogland, P.-A. Binz, R.D. Appel. The Make 2D-DB II Package. Conversion of federated 2-DE gel databases into a relational format and interconnection of distributed databases. Proteomics 3:1441-1444 (2003) (PMID 12923769)
-P33: P.-A. Binz, F. Abdi, M. Affolter, L. Allard, J. Barblan, S. Bhardwaj, W.V. Bienvenut, P. Bulet, J. Burgess, O. Carrette, G. Corthals, F. Delalande, H. Diemer, P. Favreau, E. Giuliano, Y. Gueguen, E. Guillaume, S. Hahner, P. Man, S. Michalet, D. Neri, D. Noukakis, P. Palagi , P. Paroutaud, D.C. Pimenta, M. Quadroni, A. Resemann, S. Richert, J. Rybak, J.-C. Sanchez, A. Scherl, S. Scheurer, U. Schweiger Hufnagel, C. Siethoff, D. Suckau, A. Van Dorsselaer, W.W. Redeker, N. Walter, R. Stöcklin. Proteomics application exercise of the Swiss Proteomics Society - Report of the SPS'02 session. Proteomics 3:1562-1566 (2003) (PMID 12923782)
-P34: D.F. Hochstrasser, G. Corthals, C. Zimmermann, A. Scherl, L. Bougueleret, J. Colinge, A. Masselot, P.-A. Binz, M. Muller, A. Bairoch, R.D. Appel, J.-C. Sanchez, K. Rose. Proteomics & Mass Spectrometry in Medicine. Proceedings of the . International Mass Spectrometry Conference, Edinburgh, August 31st - September 5th, 2003 (2003)
-P35: P.-A. Binz, S. Paesano, P. Zanini, A. Scherl, C. Hoogland, L. Allard, C. Zimmermann, O. Carrette, J.-C. Sanchez, S. Borella, R. Castelnovo, R.D. Appel, D.F. Hochstrasser. Why and How? A LIMS in a proteomics research environment. Proc. Swiss Proteomics Society 2003 Congress, Understanding biological systems through proteomics, Basle, 2-4 December 2003, ed. Fontis Media (ISBN 2-88476-004-0), (2003), pp 170-171
-P36: M. Tuloup, C. Hernandez, I. Coro, C. Hoogland, P.-A. Binz, R.D. Appel. Aldente and BioGraph : An improved peptide mass fingerprinting protein identification environment. Proc. Swiss Proteomics Society 2003 Congress, Understanding biological systems through proteomics, Basle, 2-4 December 2003, ed. Fontis Media (ISBN 2-88476-004-0), (2003), pp 174-176
-P37: P.-A. Binz, R.D. Appel, D.F. Hochstrasser. Mass Spectrometry Based Proteomics: Current Status and Potential Use in Clinical Chemistry. Clin Chem Lab Med 41, 1540-1551 (2003) (PMID 14708878) (Abstract)
-P38: P.-A. Binz. Mass spectrometry in proteomics. In: Genomics, Proteomics and Vaccines. Guido Grandi Ed. Wiley Publishers. ( ISBN: 0-470-85616-5), (2004), pp261-295
-P39: P.-A. Binz, M. Müller, C. Hoogland, C. Zimmermann, C. Pasquarello, G. Corthals, J.-C. Sanchez, D.F. Hochstrasser, R.D. Appel. The molecular scanner: concept and developments. Curr Op Biotechnol 15, 17-23 (2004) (PMID 15102461)
-P40: P.-A. Binz, H. Hermjakob, P. Van der Vet. Conference report: The ESF Programme on Integrated Approaches for Functional Genomics. Workshop on “Data Integration in Functional Genomics: Application to Biological Pathways”. Comparative and Functional Genomics 5, 148-155 (2004)
-P41: M. Hilario, A. Kaloukis, J. Prados, P.-A. Binz. Data mining for mass spectra-based cancer diagnostics and biomarker discovery. Biosilico 2, 214-222 (2004)
-P42: Hochstrasser D.F., Corthals G., Zimmerman C., Scherl A., Bougueleret L., Collinge J., Masselot A., Binz P.-A., Müller M., Bairoch A., Appel R.D., Sanchez J.-C., Rose K. Proteomics & Mass Spectrometry in Medicine. In: Advances in Mass Spectrometry (AE Ashcroft, G. Brenton, JJ Monhagan, Eds), Elsevier B.V., pp. 19-32.
-P43: S. Orchard, H. Hermjakob, P.-A. Binz, C. Hoogland, C.F. Taylor, W. Zhu, R.K. Julian Jr., R. Apweiler. Further steps towards data standardisation: The Proteomic Standards Initiative HUPO 3rd annual congress, Beijing 25-27th October, 2004. Proteomics 5, 337-339 (2005) (PMID: 15700244)
-P44: Scherl A, Zimmermann-Ivol CG, Di Dio J, Vaezzadeh AR, Binz PA, Amez-Droz M, Cochard R, Sanchez JC, Gluckmann M, Hochstrasser DF. Gold coating of non-conductive membranes before matrix-assisted laser desorption/ionization tandem mass spectrometric analysis prevents charging effect. Rapid Commun Mass Spectrom. 19, 605-10 (2005) (PMID: 15685683)
-P45: Palagi P.M., Walther D., Quadroni M., Catherinet S.,
Burgess J., Zimmermann-Ivol C.G., Sanchez J.C., Binz P.-A.,
Hochstrasser D.F.,
Appel R.D. MSight: an image analysis software for LC-MS. Proteomics 5,
2381-4 (2005) (PMID: 15880814)
-P46: Stephan C, Hamacher M, Bluggel M, Korting G, Chamrad D, Scheer C, Marcus K, Reidegeld KA, Lohaus C, Schafer H, Martens L, Jones P, Muller M, Auyeung K, Taylor C, Binz PA, Thiele H, Parkinson D, Meyer HE, Apweiler R. 5th HUPO BPP Bioinformatics Meeting at the European Bioinformatics Institute in Hinxton, UK--Setting the analysis frame. Proteomics. 2005 Sep;5(14):3560-2. (PMID: 16167371)
-P47: Orchard S, Hermjakob H, Taylor C, Binz PA, Hoogland C, Julian R, Garavelli JS, Aebersold R, Apweiler R. Autumn 2005 Workshop of the Human Proteome Organisation Proteomics Standards Initiative (HUPO-PSI) Geneva, September, 4-6, 2005. Proteomics 2006 Feb;6(3):738-41. (PMID 16411267)- Binz P.-A. A panel of new technologies for protein and proteome analysis, TIBTECH 18, 362. Review of Proteome and Protein Analysis (Kamp RM, Kyriakidis D. and Choli-Papadopoulou T. eds.), Springer Verlag, 1999
- Comparative and Functional Genomics 2004: A Special Section of articles from the ESF Programme on Functional Genomics workshop ‘Data integration in functional genomics and proteomics: application to biological pathways’ Held at the Swiss Institute of Bioinformatics (SIB), 22 - 24 September, 2003
- Binz P.-A., Hale, T.H., Kägi J.H.R. (1994) Metallothioneins: sequence alignment and evolution, 26th annual meeting of the USGEB/USSBE, Berne (P)
- Binz P.-A., Kägi J.H.R. (1994, 1995 and 1996) Chiroptical properties of metallothionein: Synthesis and spectroscopic characterisation of model metal-thiolate complexes, CHiral2 first, second and third Workshop (CHiral2,SNF Priority Project), Gwatt (P+T)
- Binz P.-A., Kägi J.H.R. (1995) Spectroscopic Characterization of Metallothionein model peptides Protein Science 4, suppl.1, p122, First European Symposium of the Protein Society, Davos (P)
- Binz P.-A., Kägi J.H.R. (1996) Molecular evolution of Class I Metallothioneins: Evidence from non-coding DNA regions, Fourth International Conference on Intelligent Systems for Molecular Biology 1996, St-Louis (USA). (P)
- Binz P.-A., Kägi J.H.R. (1997) Molecular evolution of Class I Metallothioneins: Contributions from coding and non-coding regions, Second European Symposium of the Protein Society, Protein Science 6, suppl. 1, p 68, Cambridge (UK). (P)
- Bogumil R., Faller P., Binz P.-A., Charnock J.M., Garner C.D., Vasak M. (1997) EXAFX study of the metal binding sites in neuronal GIF, Fall Meeting of the Gesellschaft für Biochemie und Molekularbiologie e.V., Tübingen (D) (P)
- Binz P.-A., Kägi J.H.R. (1997) Molecular evolution of the metallothionein. Suggestions for a natural classification system, Fourth International Meeting on Metallothionein, Kansas City (USA) (T)
- Bienvenut W., Wilkins M.R., Binz P.-A., Appel R.D., Sanchez J.-C., Rose K., Hochstrasser D.F. (1997) Towards the automation of protein analysis by mass spectrometry, Electrophoresis meeting, Strassbourg (F) (P)
- Binz P.-A. Cyber proteomic tools: what's available to predict protein structure. "Realizing the Commercial Potential of Proteomics: Integrating Proteomics with Genomics to Accelerate Drug Discovery", A Global Buisness Research symposium at Hyatt Sainte Claire, San Jose (CA), May 7-8, 1998. ( Symposium home page) (T)
- Bienvenut W., Binz P.-A., Appel R. D., Sanchez J.-C., K. Rose, J.-L. Veuthey, Hochstrasser D.F. Parallel protein chemical processing during transblot. 3rd Siena 2D electrophoresis meeting, Siena, Italy, Aug. 31 Sept. 3, 1998. (T)
- Binz P.-A., Bienvenut W., Fabbretti R., Gasteiger E., Bairoch A., Appel R. D., Sanchez J.-C., Hochstrasser D.F. The "molecular scanner": an highly automated methos for protein identification and 2-D PAGE annotation. 3rd Siena 2D electrophoresis meeting, Siena, Italy, Aug. 31 Sept. 3, 1998. (T)
- Fabbretti R., Binz P.-A., Bienvenut W., Gasteiger E., Bairoch A., Wilkins M.R., Sanchez J.-C., Walther D., Hochstrasser D.F., Appel R. D. Towards fully automated identification of proteins on 2-D PAGE gels. 3rd Siena 2D electrophoresis meeting, Siena, Italy, Aug. 31 Sept. 3, 1998. (P)
- Sanchez J.-C., Frutiger S., Hughes G., Hoogland C., Appel R.D., Binz P.-A., Hochstrasser D.F, Cowthorne M.. The mouse SWISS-2DPAGE database: a bridge between genomic and phenomic analysis of non-insulin-dependent diabetes-mellitus. 3rd Siena 2D electrophoresis meeting, Siena, Italy, Aug. 31 Sept. 3, 1998. (T)
- Tonella L., Walsh B.J., Sanchez J.-C., Ou K., Wilkins M., Tyler M., Frutiger S., Binz P.-A., Gooley A.A., Pescaru I., Appel R., Yan J.X., Bairoch A., Hoogland C., Hughes G.J., Williams K.L., Hochstrasser D.F. `98 Escherichia coli SWISS-2DPAGE database update. 3rd Siena 2D electrophoresis meeting, Siena, Italy, Aug. 31 Sept. 3, 1998. (T)
- Wilkins M.R., Gasteiger E., Sexton D.K., Herbert B.R., Molloy M.P., Ou K., Binz P.-A., Bairoch A., Appel R. D., Gooley A.A., Hochstrasser D.F., Williams K.L. Protein modifications, processing and identification in proteomics projects. 3rd Siena 2D electrophoresis meeting, Siena, Italy, Aug. 31 Sept. 3, 1998. (T)
- Bienvenut W., Binz P.-A., Sanchez J.-C., Appel R.D., Rose K., Veuthey J.-L., Hochstrasser D.F. Towards a molecular scanner for proteome research: Digestion of all proteins of a 2-D PAGE and identification with MALDI-MS. Congrès de la Société Suisse de Chimie Clinique, Gstaad, Oct. 1st 1998. (T)
- Bienvenut W., Binz P.-A., Appel R.D., Sanchez J.-C., Veuthey J.-L., Hochstrasser D.F. Towards a molecular scanner for proteome research: parallel protein chemical processing during transblot. Congress of the Swiss Electrophoresis Society, Basle, Dec. 3rd 1998. (P)
- Tonella L., Sanchez J.-C., Binz P.-A., Appel R.D., Bairoch A., Hoogland C., Hochstrasser D.F. New strategies in the Escherichia coli proteome analysis: a combination of one unit pH range IPGs and peptide mass fingerprinting. Congress of the Swiss Electrophoresis Society, Basle, Dec. 3rd 1998. (P)
- Binz P.-A. The molecular scanner and SWISS-2DPAGE: a highly automated method for protein identification and proteome database annotation. American Society of Cell Biology 38th annual meeting, San Francisco, Dec. 12-16 1998. (T)
- Binz P.-A. Bioinformatic tools. ESF/EMRC Workshop "Proteome Analysis in Medical Research", Feb. 5-7, 1999, Chamonix (F) (T) ( ESF report)
- Hochstrasser D., Appel R., Bienvenut W., Binz P.A., Chiappe D., Demalte I., Jung E., Sanchez J.Ch. Proteomic compexity and computational aspects in oncology. Journal of Cancer Research and clinical Oncology, supplement to vol. 125, Scientific Proceeding (abstracts), Tenth Symposium of the Division of Experimental Cancer Research (AEK) of the German Cancer Society, Heidelberg, Germany, 24-26 mars 1999 (T)
- Binz P.-A. Bioinformatics tools in proteome analysis. Journée Thématique PROTEOMIQUE, Toulouse (F), 1st Mar 1999 (T)
- Hochstrasser D.F., Appel R., Bienvenut W., Binz P.-A., Muller M., Rouge V., Tonella L., Sanchez J.-C. Present status of proteomics. Biochemical society transactions, Glasgow 7-9 April 1999 (T)
- Hochstrasser D., Sanchez J-C., Fabretti R., Müller M., Gasteiger E., Bienvenut W., Rosselat G., Binz P-A., Bairoch A., Appel R. Proteome research and its impact on laboratory medicine. WorldLab 99, Florence, June 6-11, 1999 (T)
- Binz P.-A. Automation in Proteomics: the robotized approach in peptide mass fingerprinting identification and the molecular scanner. ESF-LESC exploratory workshop on Tehnologies for Functional Genomics, Hinxton Hall, Cambridge, 15-18 Sep. 1999 (T)
- Binz P.-A. Proteomics and Automation: A Robotized Approach and the Molecular Scanner, Symposium on Chemical and Pharmaceutical Structure Analysis (CPSA), Princetown, New Jersey, 21-22 Sep. 1999 (T)
- Hochstrasser D.F., Binz P.-A., Bairoch A., Appel R.D., Sanchez J.-C. From genome to proteome: a new look at Nature complexity. Miami conference, September 1999 (T)
- Binz P.-A., W. Bienvenut, M. Müller, R. Gras, E. Gasteiger, R. Fabbretti, C. Hoogland, A. Karmime, S. Paesano, G. Rossellat, V. Rouge, L. Tonella, A. Bairoch, R. Appel, J.-C. Sanchez, D.F. Hochstrasser Automation in Proteomics: the molecular scanner and the robotization of protein identification by peptide mass fingerprinting. 3ème journée d'interaction des groupes de recherche des facultés de médecine de Genève et Lausanne, Station agronomique fédérale de Changins, 7th Oct. 1999 (P)
- Hochstrasser D.F., Sanchez J.-C., Binz P.-A., Bienvenut W., Gasteiger E., Muller M., Gras R., Fabretti R., Appel R.D. The role of virtual or computer "dry" laboratory in proteomics. 31st annual meeting of the USGEB/USSBE, Conventin Center Basel, 14-15 Oct. 1999 (T)
- Appel R.D., Bairoch A., Walther D., Binz P.-A., Hoogland Ch., Fabbretti R., Palagi P., Bouchet G., Gras R., Mueller M., Gay S., Gasteiger E., Sanchez J.-C., Hochstrasser D.F.. Improving, accelerating and automating proteomics discovery with bioinformatics. Electrophosesis'99 Forum, Meeting of the German Electrophoresis Society, Munich (D), October 25 - 27, 1999 (T)
- Hochstrasser D.F., Binz P.-A., Bairoch A., Appel R.D., Sanchez J.-C. From Genome to Proteome: a New Look at Nature Complexity. Electrophoresis'99 Forum, Meeting of the German Electrophoresis Society, Munich (D), October 25 - 27, 1999 (T)
- Hochstrasser D.F., Binz P.-A., Bienvenut W., Mueller M., Walther D., Gras R., Hoogland Ch., Bouchet G., Gasteiger E., Fabbretti R., Gay S., Palagi P., Wilkins M., Rouge V., Tonella L., Paesano S., Rossellat G., Karmime A., Bairoch A., Appel R.D., Sanchez J.-C., Proteomics Technology Development in Geneva. Elektrophorese Forum'99, Munich, October 1999 (T)
- Binz P.-A. Bioinformatics tools. HMR - Aventis R&T Proteomics Workshop, Lindner Congress Hotel, Frankfurt (D), Nov. 2nd, 1999 (T)
- Appel R.D., Bairoch A., Walther D., Binz P.-A., Hoogland Ch., Fabbretti R., Palagi P., Bouchet G., Gras R., Mueller M., Gay S., Gasteiger E., Sanchez J.-C., Hochstrasser D.F. Improving Proteomics Discovery with Bioinformatics. Swiss Electrophoresis Society (CHEL) meeting, Montreux Palace, Dec. 2nd 1999 (T)
- Bienvenut W., Binz P.-A., Rouge V., Paesano S., Heller M., Rose K., Sanchez J.-C., Hochstrasser D. Toward a clinical molecular scanner for proteome research: parallel protein chemical processing before and during western blot. Journée de la Faculté de Médecine de l'Université de Genève, Cartigny, Jan. 27th 2000 (P)
- R.D. Appel, D. Walther, P.-A. Binz, Ch. Hoogland, R. Fabbretti, P. Palagi, G. Bouchet, R. Gras, M. Mueller, S. Gay, E. Gasteiger, A. Bairoch, J.-C. Sanchez, D.F. Hochstrasser. High-throughput proteomics: the need for high-performance computing. 27th SPEEDUP Workshop, Lugano, Switzerland, March 16 - 17, 2000 on SCIENTIFIC DATA MANAGEMENT AND UNDERSTANDING IN COMPUTATIONAL SCIENCE (T)
- Hochstrasser D.F., Binz P.-A., Mueller M., Walther D., Bienvenut W., Gras R., Hoogland Ch., Bouchet G., Gasteiger E., Fabbretti R., Gay S., Palagi P., Wilkins M., Rouge V., Tonella L., Paesano S., Rossellat G., Karmime A., Bairoch A., Sanchez J.-C., Appel R.D. MALDI-TOF "Imaging": a Molecular Scanner for Proteomic Research ABRF 2000 (T)
- Appel R.D., Walther D., Binz P.-A., Hoogland Ch., Gras R., Hochstrasser D.F. Le rôle de la bioinformatique en protéomique. Atelier de formation INSERM n°115 - Le protéome: nouvelles approches expérimentales et systèmes étudiés, Jouy-en-Josas, 3-4 mai 2000 (T)
- P.-A. Binz Bioinformatics and Automation in Proteomics. Atelier de formation INSERM n°115 - Le protéome: nouvelles approches expérimentales et systèmes étudiés, Jouy-en-Josas, 3-4 Mai 2000
- D.F.Hochstrasser, J.-C. Sanchez, P.-A. Binz, W. Bienvenut, R.D. Appel. Analytical techniques for proteome research. 11th International Symposium on Pharmaceutical and Biomedical Analysis PBA 2000, Basel, May 14-18 2000
- M. Heller, W.V. Bienvenut, S. Paesano, P.-A. Binz, J.-C. Sanchez, L.B. Areces, S. Gygi, B. Rist, R. Aebersold, M. Müller, D.F. Hochstrasser. Quantitative and comprehensive one step proteome analysis by the molecular scanner coupled with ICAT technology. 48th ASMS Conference on Mass Spectrometry and Allied Topics, June 11 - 15, 2000, Long Beach Convention Center, Long Beach, California (P)
- Palagi P.M., Binz P.-A., Bairoch A., Hochstrasser D.F., Appel R.D. Bioinformatics challenges in proteomics. Symposium " Bioinformatics and proteomics ", Seoul, Korea, June 15, 2000 (T)
- W.V. Bienvenut, M. Heller, M. Müller, S. Paesano, R. Gras, P.-A. Binz, V. Converset, R.D. Appel, J.-C. Sanchez, D.F. Hochstrasser. Comprehensive one step proteome analysis by the molecular scanner: Quantitative evaluation. Fourth Siena 2D electrophoresis meeting. From Genome to Proteome Knowledge Acquisition and Representation - Siena, Italy, 4-7 Sept 2000 (T)
- C. Sarto, P.-A. Binz, S. Paesano, G. Doro, D.F. Hochstrasser, P. Mocarelli. Manganese Superoxide Dismutase Forms Post-translationally modified In Human Renal Cell Carcinoma. Fourth Siena 2D electrophoresis meeting. From Genome to Proteome Knowledge Acquisition and Representation - Siena, Italy, 4-7 Sept. 2000 (P)
- P.-A. Binz, E. Gasteiger, R. Gras, C. Hoogland, M. Müller, D. Walther, W. Bienvenut, C. Zimmermann, J.-C. Sanchez, A. Bairoch, R.D. Appel, D.F. Hochstrasser. Informatics of Proteomics and Possible Use in Laboratory Sciences. Computation in Clinical Laboratory 2000 Third Millenium CCL, Milano, Sept. 21-23, 2000 (T)(Presentation)
- Bienvenut W.V., Müller M., Paesano S., Gras R., Binz P.-A., Converset V., Déon C., Appel R.D., Sanchez J.-C., Hochstrasser D.F. Comprehensive proteome analysis: the molecular scanner. Congrès commun des sociétés de biochimie française et italienne, Siène, 26-29 septembre 2000
- Palagi P.M., Hoogland Ch., Gras R., Mueller M., Binz P.-A., Fabbretti R., Bouchet G., Walther D., Gay S., Gasteiger E., Bairoch A., Sanchez J.-C., Hochstrasser D.F., Appel R.D. Human proteomics and bioinformatics tools. The first draft of the human genome : an academic and industrial perspective, Berlin, Germany, October 1 - 2, 2000 (T)
- P.-A. Binz. Peptide mass fingerprinting - The molecular scanner. PROTEOMICS : TOOLS FOR THE POST-GENOME ERA. ISREC - Ludwig Institute, Epalinges (CH), 20th October 2000 (T)
- E. Baas, P.-A. Binz. Bioinformatics in Large Scale Proteome Production. IBC conference Proteomics, Functional Genomics, Bioinformatics. The Wigwam Resort, Litchfield Park, Phoenix, AZ. 16-17th October 2000 (T)
- P.-A. Binz, A. Bairoch, J.-C. Sanchez, D.F. Hochstrasser, R.D. Appel. Bioinformatics Challenges in Proteomics. MIPTEC-ICAR, Convention Center, Basel, October 30 - November 2, 2000 (T)
- Hochstrasser D.F., Bienvenut W., Muller M. Gras R., Binz P.-A., Appel R.D., Sanchez J.C. From Genome to Proteome: the development of a molecular scanner Colloque AcM/MdA - Acquisition conduite par le Modèle - Model driven Acquisition, Grenoble, 23-24 novembre 2000 (T)
- P.-A. Binz, E. Gasteiger, R. Gras, C. Hoogland, M. Müller, D. Walther, W. Bienvenut, J.-C.Sanchez, A. Bairoch, R.D. Appel, D.F. Hochstrasser. The bioinformatics needs and challenges in proteomics. Winter Student School on Current Trends in Physicochemical Biology, Moscow, February 7-9, 2001 (T)
- P.-A. Binz, E. Gasteiger, C. Hoogland, M. Müller, R. Gras, S. Gay, R.D. Appel, D.F. Hochstrasser. Bioinformatics needs in proteomics: handling, understanding and interpreting experimental data. II Jornadas de Bioinformatica. Malaga, May 30- June 1, 2001 (T)
- P.-A. Binz. EMBO course Advanced bioinformatic techniques in genomics, transcriptomics and proteomics. Uppsala (S), Aug 26 - Sep 2nd, 2001 (C) (Course and practicum, see the schedule)
- P.-A. Binz. Bioinformatics and the complexity of proteomics. Summer course "New technologies in biomedicine". El Escorial (E), Sep 5-7th, 2001 (T)
- P.-A. Binz. Analyse des protéines par spectrométrie de masse: nouvelles dimensions. Assemblée générale SSCC/SGKC, Martigny (CH), Sept 25 - 29, 2001 (T)
- P.-A. Binz. Proteomatics: bioinformatic tools and databases in proteomics. Symposium "Protéomique: approche technique et analyse fonctionnelle". Nice(F), Sept 28-29th, 2001 (T)
- D.F. Hochstrasser, P.-A. Binz. Proteomics Perspective: components, status. Conferences Philippe Laudat, Aix-les-Bains (F), Oct 7-11th, 2001 (T)
- P.-A. Binz, D.F. Hochstrasser, R.D. Appel. Large scale proteomics: are high-throughput and high-confidence compatible? Metrologie 2001, St-Louis (F), Oct 22-25th, 2001 (T)
- P.-A. Binz. Bioinformatics needs to unravel proteomics complexity. EuroLabAutomation 2001, London, Oct 23-25, 2001 (T)
- P.-A. Binz. The need for bioinformatics in proteomics. Applied Biosystems European Presentation Tour, 18-22 March 2002, Eindhoven (NL), Stockholm (S), Mannheim (D), Paris (F) (T)
- W.V. Bienvenut, M. Müller, S. Paesano, P.-A. Binz, V. Converset, G. Corthals, J.-C. Sanchez, D.F. Hochstrasser. A new method for large-scale proteins identification: the molecular scanner. VIIeme colloque de l'associattion des doctorants du centre de Biophysique moléculaire d'Orléans, Orleans (F), May 2002 (T)
- P.-A. Binz. Quels outils bioinformatiques lors d'une analyse protéomique? Quelques exemples. Congrès SPTC-SFT-SFTG 2002, Paris (F), May 23-24, 2002 (T)
- R. Gras, M. Muller, D. Hernandez, P. Hernandez, N. Zangger, P. Palagi, P.-A. Binz , F. Lisacek, R. Appel. New approaches of computational proteomics. JOBIM, Saint-Malo (F), June 10-12, 2002 (T)
- P.-A. Binz. Bioinformatique pour la protéomique: quelques morceaux choisis. Journée Scientifique SFEAP (Société Française d'Electrophorèse et d'Analyse Protéomique), Inst. Pasteur, Paris (F), June 13, 2002 (T)
-P.-A. Binz, W. Bienvenut, M. Müller, R. Gras, J.-C. Sanchez, C. Pasquarello, G. Corthals, T. Nadler, G. Vella, Y. Huang, B. Wagenfeld, K. Parker, R. Lotti, D.F. Hochstrasser, R.D. Appel. Le scanner moléculaire et ses applications. IFR 65 "Cancer, Inflamation, Hormones", séminaire thématisé "Analyse Protéomique", Paris (F), June 18, 2002 (T)
- D.F. Hochstrasser, J.-C. Sanchez, G. Corthals, P.-A. Binz, M. Mueller, D. Walther, R.D. Appel. Bioinformatics for Proteomics. International Conference "Genomics, Proteomics and Bioinformatics for Medicine" (gpbm2002), Moscow, 22-30 June 2002 (T)
- R.Gras, M. Müller, D. Hernandez, P. Hernandez, N. Zangger, P. Palagi, P.-A. Binz, R.D. Appel. Cooperative metaheuristic for proteomics. 13th International Symposium, ISMIS 2002, Lyon, France, June 27-29, 2002 (T)
- P.-A. Binz. Bioinformatics Analysis of Proteomic Data. Avances en proteomica: introduccion a la bioinformatica en proteomica. Cursos de Verano, San Lorenzo El Escorial (SP), August 26-20 2002, (C)
- M. Müller, R. Gras, W.V. Bienvenut, P.-A. Binz, C. Pasquarello, D.F. Hochstrasser, R.D. Appel. Using Peptide Signal Intensity Distributions for a Better Interpretation of Molecular Scanner Data. 5th Siena Meeting From Genome to Proteome: functional proteomics, Siena (I), Sept. 2-5 2002 (T)
- T. Nadler, Y. Huang, B. Wagenfeld, K. Parker, R. Lotti, G.J. Vella, P.-A. Binz, M. Müller, R. Gras, D.F.Hochstrasser, W. Bienvenut, J.-C. Sanchez, G. Corthals, R.D. Appel. Proteome Analysis by Multi-Dimensional Liquid Chromatography Gel-Electrophoresis and the Molecular Scanner. 5th Siena Meeting From Genome to Proteome: functional proteomics, Siena (I), Sept. 2-5 2002 (T)
- W. Bienvenut, P.-A. Binz, J.-C. Sanchez, D.F. Hochstrasser. Molecular scanner project: Optimisation of the matrix deposition; alpha-cyano-4-hydroxy cinnamic acid solubility in various solvents. 5th Siena Meeting From Genome to Proteome: functional proteomics, Siena (I), Sept. 2-5 2002 (P)
- K. Mostaguir, C. Hoogland, P.-A. Binz, R.D. Appel. The Make 2D-DB II Package - Conversion of federated 2-DE gel databases into a relational format and Interconnection of distributed databases. 5th Siena Meeting From Genome to Proteome: functional proteomics, Siena (I), Sept. 2-5 2002 (P)
- G. Corthals, G. Schmidt, A. Scherl, W. Bienvenut, P.-A. Binz, S. Voordijk, R. Appel, J.-C. Sanchez. Proteomics: tools and applications. Pharamacogenomics: Improving pharmacotherapy and Avoiding Adverse Drug Reactions. The Association of Clinical Biochemists, Cambridge (UK), Sept 26-27th, 2002 (T)
- P.-A. Binz, M. Müller, C. Hoogland, D. Walther, S. Gay, R. Gras, W.V. Bienvenut, C. Pasquarello, S. Paesano, G. Corthals, J.-C. Sanchez, A. Bairoch, D.F. Hochstrasser, R.D. Appel. The Synergy between Bioinformatics and Proteomics Research. Annual Meeting of the Danish Society for Biochemistry and Molecular Biology; Oct 30th, 2002 (T) (Abstract)
- R.D. Appel, P. Hernandez, M. Tuloup, D. Walther, R. Gras, M. Müller, C. Hoogland, P.-A. Binz, G. Corthals, J.-C. Sanchez, D.F. Hochstrasser. Some new developments in proteomatics at the Swiss Institute of Bioinformatics. HUPO First World Congress, Versailles (F), Nov. 21-24 2002 (T)
- P.-A. Binz, S. Gay, D.F. Hochstrasser, R.D. Appel. Knowledge Discovery to understand and predict peptide mass fingerprinting spectra. HUPO First World Congress, Versailles (F), Nov. 21-24 2002 (P)
- M. Tuloup, C. Hoogland, P.-A. Binz, R.D. Appel. A new Peptide Mass Fingerprinting tool on ExPASy : ALDentE. Swiss Proteomics Society 2002 congress: Applied Proteomics, Lausanne (CH), Dec. 3-5 2002 (P)
- K. Mostaguir, C. Hoogland, P.-A. Binz, R.D. Appel. The Make 2D-DB II Package - Conversion of federated 2-DE gel databases into a relational format and interconnection of distributed databases. Swiss Proteomics Society 2002 congress: Applied Proteomics, Lausanne (CH), Dec. 3-5 2002 (P)
- G.L. Corthals, C. Pasquarello, A. Scherl, J. Burgess, L. Allard, J. Deshusses, N. Walter, S. Paesano, O. Carrette, W. Bienvenut, C. Hoogland, P.-A. Binz, M. Müller, R.D. Appel, D.F. Hochstrasser, J.-C. Sanchez. Tools and technologies in proteome analysis. Swiss Proteomics Society 2002 congress: Applied Proteomics, Lausanne (CH), Dec. 3-5 2002 (T)
- P.-A. Binz, C. Hoogland. Data management. Short course in proteomics: "Proteomics data interpretation and management - from data to biology". Swiss Proteomics Society 2002 congress: Applied Proteomics, Lausanne (CH), Dec. 3-5 2002 (C)
- P.-A. Binz. The contribution of bioinformatics in proteomics workflows. Applied Biosystems seminar, London, 29 May 2003 (T)
- G.L. Corthals, C. Pasquarello, A. Scherl, J. Burgess, A. Vaezzadeh, J. Deshusses, D.F. Hochstrasser, J.-C. Sanchez, P.-A. Binz, R.D. Appel. Controlling data acquisition and data quality in proteomics via ordered peptide arrays and non-redundant mass-spectrometry. MIPTEC, Basel (CH), May 12-15, 2003 (T)
- P.-A. Binz, G. Bologna, S. Gay, C. Hernandez, C. Hoogland, K. Mostaguir, M. Tuloup, R.D. Appel. Bioinformatics tools in proteomics: issues and perspectives. Functional Genomics and Disease, Prague (CZ), May 14-17, 2003 (T). (Abstract)
- Hochstrasser D.F., Sanchez J.-C., Corthals G., Binz P.-A., Müller M., Appel R.D., Bougueleret L. and Rose K. Proteomics in laboratory medicine. EUROMEDLAB Barcelona 2003, 15th IFCC - FESCC European Congress of Clinical Chemistry and Laboratory Medicine, Barcelona, june 2003.
- P.-A. Binz, G. Bologna, S. Gay, C. Hernandez, M. Tuloup, P. Hernandez, R.D. Appel. Identification and characterization of proteins using mass spectrometry: what tools, what challenges? IBC congress Basle, 1st July 2003 (T)
- P.-A. Binz. On the complexity of proteome analysis. European Congress in Biotechnology (ECB11), Basle (CH), Aug 24-29, 2003 (T) ( Abstract)
- P.-A. Binz, S. Paesano, P. Zanini, A. Scherl, C. Hoogland, L. Allard, C. Zimmermann, O. Carrette, J.-C. Sanchez, S. Borella, R. Castelnovo, R.D. Appel, D.F. Hochstrasser. Why and How? A LIMS in a proteomics research environment. Swiss Proteomics Society 2003 congress, Understanding biological systems through proteomics, Basle(CH), Dec. 2-4 2003 (P)
- M. Tuloup, C. Hernandez, I. Coro, C. Hoogland, P.-A. Binz, R.D. Appel. Aldente and BioGraph : An improved peptide mass fingerprinting protein identification environment. Swiss Proteomics Society 2003 congress, Understanding biological systems through proteomics, Basle(CH), Dec. 2-4 2003 (P)
- P.-A. Binz, R. D. Appel. La qualité des données et des résultats en analyse protéomique. Séminaire Protéomique Applied Biosystems, Paris, 15 January, 2004 (T)
- R.D. Appel, P.-A. Binz, G. Bouchet, S. Catherinet, R. Gras, C.
Hernandez,
D. Hernandez, P. Hernandez, C. Hoogland, F. Lisacek, K.
Mostaguir,
M. Müller, P. Palagi, S. Pelhatre, M. Tuloup, D. Walther, N.
Zangger.
Current developments at the Proteome Informatics Group, Swiss Institute
of Bioinformatics, Geneva. Quelle
informatique et bioinformatique pour la protéomique ?
Journée
organisée par Rhône-Alpes Genopole, INRIA
Rhône-Alpes,
Montbonnot (Grenoble, F), Jun 1 2004 (T)
- P.-A. Binz, A. Masselot, L. Cambria, M. Müller, M.
Tuloup,
C. Hernandez, R.D. Appel. Phenyx: About compatibility of
High-Throughput
and Pertinence in Protein Identification. IV Siena meeting from Genome
to Proteome iomarker discovery & proteome imaging, Siena (I), Aug
29-Sept
2 2004 (T)
- P.-A. Binz,
D. F. Hochstrasser. Future trends in
clinical proteomics. First of all: Can you believe in your data?
3rd Swedish
Proteomics Society Symposium,
Lund, Oct 4th 2004 (T)
- P.-A. Binz, A. Masselot, L. Cambria, M. Müller, M. Tuloup, C. Hernandez, D. Walther, S. Catherinet, R.D. Appel. Bioinformatics and relevance in proteomics. SFEAP Bordeaux (F), Oct. 14-15 2004 (T)
- A. Masselot, P.-A. Binz, L. Cambria, R.D. Appel. Phenyx: combining high-throughput and pertinence in protein identification. HUPO 2004, Beijing, Oct 25-27 2004 (P)
- A. Scherl, C.G. Zimmermann-Ivol, J. Di Dio, A. Vaezzadeh, P.-A. Binz, M. Amez-Droz, R. Cochard, M. Glückmann, D.F. Hochstrasser. Gold coating of non-conducting membranes before Matrix Assisted Laser Desorption Ionisation prevents charging effect. Proc of the Swiss Proteomics Society 2004 congress, Proteomics for Health, Bern (CH), Dec. 6-8 2004 (P)
- D. Walther, M. Quadroni, S. Catherinet, M. Tuloup, P.-A. Binz, J.
Burgess, C.G. Zimmermann-Ivol, J.-C. Sanchez, D.F. Hochstrasser, R.D.
Appel. Proteome imaging: a prerequisite for any MS-related
proteomic
study? Proc of the Swiss
Proteomics
Society 2004
congress, Proteomics for Health, Bern (CH), Dec. 6-8 2004 (T)
- Masselot A., Binz P.-A.,
Cambria L., Appel R.D. Phenyx:
Manage Protein Identification With Flexibility and Pertinence. Proc of
the Swiss
Proteomics
Society 2004
congress, Proteomics for Health, Bern (CH), Dec. 6-8 2004 (P)
- D. Walther, Patricia M. Palagi, M. Quadroni, S. Catherinet, P.-A. Binz, D.F. Hochstrasser, R.D. Appel. MSight: an LC-MS image analysis software. ISMB 2005 Academic demo (T)
- Hochstrasser DF,
Scherl A, Binz PA, Zimmerman C, Sanchez JC, Appel RD. Complex Specimen
struggling to survive. BSPR/EBI Meeting – From Proteins to
Systems. Cambridge: July 2005. (T)
- Binz PA,
Masselot A, Walther D, Appel RD.
Interpretation of protein
identification results: more questions than answers? The confidence and
validation issue. BSPR/EBI Meeting – From Proteins to Systems.
Cambridge: July 2005. (T)
- Hochstrasser DF,
Appel RD, Paesano S, Binz PA, Sanchez JC, Zimmermann C. Proteomics
& Clinical Chemistry. Fourth HUPO annual meeting. Munich:
Aug. 2005. (T)
- Binz PA, Masselot A, Budin N, Nahas N. Discover Multiple Facets of the Innovative Phenyx Platform and Achieve Increased Confidence in Protein Identification. HUPO 4th Annual Congress Munich, August 2005 (T)
- Appel RD, Masselot A, Budin N, Evalet O, Cambria L, Binz PA. What’s in MS spectra? What’s in databases? Take the best to identify active proteins. Fourth HUPO annual meeting. Munich: Aug. 2005.
- Binz P.-A., Masselot A., Appel R.D. Proteome Bioinformatics: critically evaluating MS data. Swiss Proteomics Society 2005 Congress: Expanding proteomics. Dec. 2005. Zurich, Switzerland: 2005 (T)| - Music | - Since 1985 1st euphonium in La
Landwehr
de Fribourg, concert and marching band, official symphonic brass
orchester
of the Town and the District of Fribourg, Switzerland - 2000-2006: trombone in the SAN Big-Band - 1983-1987: Co-foundator of the entertainment brass group "Belzé Blues Band" - 1980-1987: trumpet and then euphonium in the "Fanfare du Collège St-Michel", Fribourg. Member of the committee between 1984 and 1987, the two last years as vice-president, |
| - Photography | Since 1981 working mainly with 135
format. Prefered interests in geometrical subjects and contrasting colors in landscapes as well as details or portraits. |
| - Dancing | Tango
Argentino About 2 years of ballroom standard and latino, as well as disco fox |
| - Snowboard | Alpin type since more than 15 years |
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