ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot ENZYME
Search for

NiceZyme View of ENZYME: EC 3.4.21.75

Official Name
Furin.
Alternative Name(s)
Dibasic processing enzyme.
Paired basic amino acid residue cleaving enzyme.
Prohormone convertase.
Reaction catalysed
Release of mature proteins from their proproteins by cleavage of -Arg-Xaa-Yaa-Arg-|-Zaa- bonds, where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors
Comment(s)
  • Activated by calcium.
  • Belongs to peptidase family S8.
Cross-references
PROSITEPDOC00125
BRENDA3.4.21.75
PUMA23.4.21.75
PRIAM enzyme-specific profiles3.4.21.75
KEGG Ligand Database for Enzyme Nomenclature3.4.21.75
IUBMB Enzyme Nomenclature3.4.21.75
IntEnz3.4.21.75
MEDLINEFind literature relating to 3.4.21.75
MetaCyc3.4.21.75
UniProtKB/Swiss-Prot
P26016, FUR11_DROME;  P30430, FUR1C_DROME;  P30432, FUR2_DROME;  
P29119, FURI1_XENLA;  Q28193, FURIN_BOVIN;  P09958, FURIN_HUMAN;  
P23188, FURIN_MOUSE;  P23377, FURIN_RAT;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot ENZYME