| Official Name |
|---|
| Scutelarin.
|
| Alternative Name(s) |
|---|
| Taipan activator. |
| Reaction catalysed |
|---|
| Selective cleavage of Arg-|-Thr and Arg-|-Ile in prothrombin to form thrombin and two inactive fragments |
| Comment(s) |
|---|
- From the venom of Taipan snake (Oxyuranus scutellatus).
- Converts prothrombin to thrombin in the absence of coagulation factor
Va, and is potentiated by phospholipid and calcium.
- Specificity is similar to that of factor Xa.
- Binds calcium via gamma-carboxyglutamic acid residues.
- Similar enzymes are known from the venom of other Australian elapid
snakes Pseudonaja textilis, Oxyuranus microlepidotus and Demansia
nuchalis affinis.
- Formerly EC 3.4.99.28.
|
| Cross-references |
|---|
| BRENDA | 3.4.21.60 |
| PUMA2 | 3.4.21.60 |
| PRIAM enzyme-specific profiles | 3.4.21.60 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.60 |
| IUBMB Enzyme Nomenclature | 3.4.21.60 |
| IntEnz | 3.4.21.60 |
| MEDLINE | Find literature relating to 3.4.21.60 |
| MetaCyc | 3.4.21.60 |
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