| Official Name |
|---|
| CO-methylating acetyl-CoA synthase.
|
| Alternative Name(s) |
|---|
| ACS. |
| Reaction catalysed |
|---|
| Acetyl-CoA + corrinoid protein <=> CO + methylcorrinoid protein + CoA |
| Cofactor(s) |
|---|
| Iron-sulfur; Nickel.
|
| Comment(s) |
|---|
- Also catalyzes exchange reactions of carbon between C-1 of acetyl-CoA
and CO, and between C-2 of acetyl-CoA and methyl corrinoid protein.
- Involved, together with EC 1.2.7.4, in the synthesis of acetyl-CoA
from CO(2) and H(2).
- To follow its stoichiometry, the reaction can be written as:
CH(3)-CO-S-CoA + protein Co(+) + H(+) = CO + protein Co(2+)-CH(3) +
HS-CoA.
|
| Cross-references |
|---|
| BRENDA | 2.3.1.169 |
| PUMA2 | 2.3.1.169 |
| PRIAM enzyme-specific profiles | 2.3.1.169 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.169 |
| IUBMB Enzyme Nomenclature | 2.3.1.169 |
| IntEnz | 2.3.1.169 |
| MEDLINE | Find literature relating to 2.3.1.169 |
| MetaCyc | 2.3.1.169 |
| UniProtKB/Swiss-Prot |
|
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