| Official Name |
|---|
| Histone-arginine N-methyltransferase.
|
| Alternative Name(s) |
|---|
| Histone protein methylase. |
| Protein methylase I. |
| Protein-arginine N-methyltransferase. |
| Reaction catalysed |
|---|
| S-adenosyl-L-methionine + histone-arginine <=> S-adenosyl-L-homocysteine + histone-N(omega)-methyl-arginine |
| Comment(s) |
|---|
- Forms the N(omega)-monomethyl- and N(omega),N(omega')-dimethyl,
but not the N(omega),N(omega)-dimethyl-arginine derivatives.
- The name protein methylase I is misleading since it has been used for
a number of enzymes with different specificities.
- Formerly EC 2.1.1.23.
|
| Cross-references |
|---|
| BRENDA | 2.1.1.125 |
| PUMA2 | 2.1.1.125 |
| PRIAM enzyme-specific profiles | 2.1.1.125 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.125 |
| IUBMB Enzyme Nomenclature | 2.1.1.125 |
| IntEnz | 2.1.1.125 |
| MEDLINE | Find literature relating to 2.1.1.125 |
| MetaCyc | 2.1.1.125 |
| UniProtKB/Swiss-Prot |
| Q8GWT4, ANM5_ARATH; | A7YW45, ANM5_BOVIN; | P46580, ANM5_CAEEL; |
| Q54KI3, ANM5_DICDI; | O14744, ANM5_HUMAN; | Q4R5M3, ANM5_MACFA; |
| Q8CIG8, ANM5_MOUSE; | A2X0Q3, ANM5_ORYSI; | Q6YXZ7, ANM5_ORYSJ; |
| Q5R698, ANM5_PONAB; | Q6DC04, CARM1_DANRE; | Q9VH48, CARM1_DROME; |
| Q86X55, CARM1_HUMAN; | Q9WVG6, CARM1_MOUSE; | A2YPT7, CARM1_ORYSI; |
| Q7XI75, CARM1_ORYSJ; | Q4AE70, CARM1_RAT; | Q5XK84, CARM1_XENLA; |
| Q84W92, CARMA_ARATH; | A3KPF2, CARMB_ARATH; | P38274, HSL7_YEAST; |
|
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