| Official Name |
|---|
| (R)-benzylsuccinyl-CoA dehydrogenase.
|
| Reaction catalysed |
|---|
| (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein <=> (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- The enzyme is highly specific for (R)-benzylsuccinyl-CoA and is
inhibited by (S)-benzylsuccinyl-CoA.
- Forms the third step in the anaerobic toluene metabolic pathway in
Thauera aromatica.
- Uses the ferricenium ion as the preferred artificial electron
acceptor.
- Unlike other acyl-CoA dehydrogenases, this enzyme exhibits high
substrate- and enantiomer specificity.
|
| Cross-references |
|---|
| PROSITE | PDOC00070 |
| BRENDA | 1.3.99.21 |
| PUMA2 | 1.3.99.21 |
| PRIAM enzyme-specific profiles | 1.3.99.21 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.3.99.21 |
| IUBMB Enzyme Nomenclature | 1.3.99.21 |
| IntEnz | 1.3.99.21 |
| MEDLINE | Find literature relating to 1.3.99.21 |
| MetaCyc | 1.3.99.21 |
| UniProtKB/Swiss-Prot |
|
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