ID   1.2.4.4
DE   3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring).
AN   2-oxoisocaproate dehydrogenase.
AN   2-oxoisovalerate (lipoate) dehydrogenase.
AN   3-methyl-2-oxobutanoate dehydrogenase (lipoamide).
AN   3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and
AN   acceptor-2-methylpropanoylating).
AN   Alpha-keto-alpha-methylvalerate dehydrogenase.
AN   Alpha-ketoisocaproate dehydrogenase.
AN   Alpha-ketoisocaproic dehydrogenase.
AN   Alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase.
AN   Alpha-ketoisovalerate dehydrogenase.
AN   Alpha-oxoisocaproate dehydrogenase.
AN   BCKDH.
AN   BCOAD.
AN   Branched chain keto acid dehydrogenase.
AN   Branched-chain (-2-oxoacid) dehydrogenase (BCD).
AN   Branched-chain 2-keto acid dehydrogenase.
AN   Branched-chain 2-oxo acid dehydrogenase.
AN   Branched-chain alpha-keto acid dehydrogenase.
AN   Branched-chain alpha-oxo acid dehydrogenase.
AN   Branched-chain keto acid dehydrogenase.
AN   Branched-chain ketoacid dehydrogenase.
AN   Dehydrogenase, 2-oxoisovalerate (lipoate).
AN   Dehydrogenase, branched chain alpha-keto acid.
CA   3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue
CA   (2-methylpropanoyl)transferase] lipoyllysine = [dihydrolipoyllysine-
CA   residue (2-methylpropanoyl)transferase]
CA   S-(2-methylpropanoyl)dihydrolipoyllysine + CO(2).
CF   Thiamine diphosphate.
CC   -!- It acts not only on 3-methyl-2-oxobutanaoate, but also on 4-methyl-2-
CC       oxopentanoate and (S)-3-methyl-2-oxopentanoate, so that it acts on
CC       the 2-oxo acids that derive from the action of transaminases on
CC       valine, leucine and isoleucine.
CC   -!- It is a component of the multienzyme 3-methyl-2-oxobutanoate
CC       dehydrogenase complex in which multiple copies of it are bound to a
CC       core of molecules of EC 2.3.1.168, which also binds multiple copies
CC       of EC 1.8.1.4.
CC   -!- It does not act on free lipoamide or lipoyllysine, but only on the
CC       lipoyllysine residue in EC 2.3.1.168.
CC   -!- Formerly EC 1.2.4.3.
DR   P37940, ODBA_BACSU ;  P11178, ODBA_BOVIN ;  Q54M22, ODBA_DICDI ;
DR   P12694, ODBA_HUMAN ;  Q8HXY4, ODBA_MACFA ;  P50136, ODBA_MOUSE ;
DR   A5A6H9, ODBA_PANTR ;  Q9I1M2, ODBA_PSEAE ;  P09060, ODBA_PSEPU ;
DR   P11960, ODBA_RAT   ;  Q72GU1, ODBA_THET2 ;  Q5SLR4, ODBA_THET8 ;
DR   P37941, ODBB_BACSU ;  P21839, ODBB_BOVIN ;  Q55FN7, ODBB_DICDI ;
DR   P21953, ODBB_HUMAN ;  Q6P3A8, ODBB_MOUSE ;  Q9I1M1, ODBB_PSEAE ;
DR   P09061, ODBB_PSEPU ;  P35738, ODBB_RAT   ;  Q72GU2, ODBB_THET2 ;
DR   Q5SLR3, ODBB_THET8 ;
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