ID 1.2.1.60 DE 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase. AN Carboxymethylhydroxymuconic semialdehyde dehydrogenase. CA 5-carboxymethyl-2-hydroxymuconate semialdehyde + H(2)O + NAD(+) = CA 5-carboxymethyl-2-hydroxymuconate + NADH. CC -!- Involved in the tyrosine degradation pathway in Arthrobacter sp. //