ID   1.2.1.45
DE   4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase.
CA   4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP(+) + H(2)O =
CA   4-carboxy-2-hydroxy-cis,cis-muconate + NADPH.
CC   -!- Does not act on unsubstituted aliphatic or aromatic aldehydes or
CC       glucose.
CC   -!- NAD(+) can replace NADP(+), but with lower affinity.
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