ID   1.17.1.5
DE   Nicotinate dehydrogenase.
AN   Nicotinate hydroxylase.
AN   Nicotinic acid hydroxylase.
CA   Nicotinate + H(2)O + NADP(+) = 6-hydroxynicotinate + NADPH.
CF   Flavoprotein; Iron.
CC   -!- The enzyme is capable of acting on a variety of nicotinate analogs to
CC       varying degrees, including pyrazine-2-carboxylate, pyrazine 2,3-
CC       dicarboxylate, trigonelline and 6-methylnicotinate.
CC   -!- The enzyme from Clostridium barkeri also possesses a catalytically
CC       essential, labile selenium that can be removed by reaction with
CC       cyanide.
CC   -!- Forms part of the nicotinate-fermentation catabolism pathway in
CC       Eubacterium barkeri.
CC   -!- Other enzymes involved in this pathway are EC 1.3.7.1, EC 3.5.2.18,
CC       EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.
CC   -!- Formerly EC 1.5.1.13.
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