| Official Name |
|---|
| Lathosterol oxidase.
|
| Alternative Name(s) |
|---|
| 5-DES. |
| Delta(7)-sterol 5-desaturase. |
| Delta(7)-sterol Delta(5)-dehydrogenase. |
| Delta(7)-sterol-C5(6)-desaturase. |
| Lathosterol 5-desaturase. |
| Reaction catalysed |
|---|
| 5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) <=> cholesta-5,7-dien-3-beta-ol + NAD(P)(+) + 2 H(2)O |
| Comment(s) |
|---|
- This enzyme catalyzes the introduction of a C5 double bond into the B
ring of Delta(7)-sterols to yield the corresponding
Delta(5,7)-sterols in mammals, yeast and plants.
- Forms part of the plant sterol biosynthesis pathway.
- Formerly EC 1.3.3.2.
|
| Cross-references |
|---|
| BRENDA | 1.14.21.6 |
| PUMA2 | 1.14.21.6 |
| PRIAM enzyme-specific profiles | 1.14.21.6 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.21.6 |
| IUBMB Enzyme Nomenclature | 1.14.21.6 |
| IntEnz | 1.14.21.6 |
| MEDLINE | Find literature relating to 1.14.21.6 |
| MetaCyc | 1.14.21.6 |
| UniProtKB/Swiss-Prot |
|
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