ID   1.14.13.39
DE   Nitric-oxide synthase.
AN   Endothelium-derived relaxation factor-forming enzyme.
AN   Endothelium-derived relaxing factor synthase.
AN   NADPH-diaphorase.
AN   Nitric-oxide synthetase.
AN   NO synthase.
CA   L-arginine + n NADPH + m O(2) = citrulline + nitric oxide + n NADP(+).
CC   -!- The enzyme in brain, but not that induced in lung or liver by
CC       endotoxin, requires calcium.
CC   -!- The stoichiometry is not clear, but may involve a two-electron and a
CC       one-electron oxidation step.
DR   Q66GP9, NOS1_ARATH ;  P29475, NOS1_HUMAN ;  Q9Z0J4, NOS1_MOUSE ;
DR   O19132, NOS1_RABIT ;  P29476, NOS1_RAT   ;  Q29498, NOS1_SHEEP ;
DR   P35228, NOS2A_HUMAN;  Q27995, NOS2_BOVIN ;  O62699, NOS2_CANFA ;
DR   Q28314, NOS2_CAPHI ;  Q92037, NOS2_CARAU ;  O54705, NOS2_CAVPO ;
DR   Q90703, NOS2_CHICK ;  O46660, NOS2_MACMU ;  P29477, NOS2_MOUSE ;
DR   Q92091, NOS2_ONCMY ;  P79290, NOS2_PIG   ;  O19114, NOS2_RABIT ;
DR   Q06518, NOS2_RAT   ;  P29473, NOS3_BOVIN ;  Q9TUX8, NOS3_CANFA ;
DR   P97270, NOS3_CAVPO ;  P29474, NOS3_HUMAN ;  P70313, NOS3_MOUSE ;
DR   Q28969, NOS3_PIG   ;  Q62600, NOS3_RAT   ;  P79209, NOS3_SHEEP ;
DR   O61608, NOS_ANOST  ;  Q27571, NOS_DROME  ;  O61309, NOS_LYMST  ;
DR   Q6YPG5, NOS_ORYSJ  ;  Q26240, NOS_RHOPR  ;  Q9I9M2, NOS_SQUAC  ;
//