| Official Name |
|---|
| Tryptophan 2'-dioxygenase.
|
| Alternative Name(s) |
|---|
| Indole-3-alkane alpha-hydroxylase. |
| Tryptophan side-chain alpha,beta-oxidase. |
| Tryptophan side-chain oxidase. |
| TSO. |
| Reaction catalysed |
|---|
| L-tryptophan + O(2) <=> (indol-3-yl)glycolaldehyde + CO(2) + NH(3) |
| Cofactor(s) |
|---|
| Heme.
|
| Comment(s) |
|---|
- Acts on a number of indole-3-alkane derivatives, oxidizing the
3-side-chain in the 2'-position.
- Best substrates are L-tryptophan and 5-hydroxy-L-tryptophan.
|
| Cross-references |
|---|
| BRENDA | 1.13.99.3 |
| PUMA2 | 1.13.99.3 |
| PRIAM enzyme-specific profiles | 1.13.99.3 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.13.99.3 |
| IUBMB Enzyme Nomenclature | 1.13.99.3 |
| IntEnz | 1.13.99.3 |
| MEDLINE | Find literature relating to 1.13.99.3 |
| MetaCyc | 1.13.99.3 |
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