| Official Name |
|---|
| 2-nitropropane dioxygenase.
|
| Alternative Name(s) |
|---|
| 2-NPD. |
| Nitroalkane oxidase. |
| Reaction catalysed |
|---|
| 2 2-nitropropane + O(2) <=> 2 acetone + 2 nitrite |
| Cofactor(s) |
|---|
| FAD or FMN.
|
| Comment(s) |
|---|
- While the enzyme from the fungus Neurospora crassa contains non-
covalently bound FMN as the cofactor, that from the yeast Williopsis
mrakii contains FAD.
- Differs from EC 1.7.3.1 in that the preferred substrates are anionic
nitronates rather than neutral nitroalkanes.
- Has broad substrate specificity that is independent of substrate
size.
- Some other nitroalkanes, including nitroethane, 1-nitropropane and
3-nitropentan-2-ol, can act as donors, but more slowly.
|
| Cross-references |
|---|
| BRENDA | 1.13.11.32 |
| PUMA2 | 1.13.11.32 |
| PRIAM enzyme-specific profiles | 1.13.11.32 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.13.11.32 |
| IUBMB Enzyme Nomenclature | 1.13.11.32 |
| IntEnz | 1.13.11.32 |
| MEDLINE | Find literature relating to 1.13.11.32 |
| MetaCyc | 1.13.11.32 |
| UniProtKB/Swiss-Prot |
|
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