| Official Name |
|---|
| (S)-2-hydroxy-acid oxidase.
|
| Alternative Name(s) |
|---|
| Glycolate oxidase. |
| Hydroxy-acid oxidase A. |
| Hydroxy-acid oxidase B. |
| Reaction catalysed |
|---|
| (S)-2-hydroxy acid + O(2) <=> 2-oxo acid + H(2)O(2) |
| Cofactor(s) |
|---|
| FMN.
|
| Comment(s) |
|---|
- Exists as two major isoenzymes; the A form preferentially oxidizes
short-chain aliphatic hydroxy acids; the B form preferentially
oxidizes long-chain and aromatic hydroxy acids.
- The rat isoenzyme B also acts as EC 1.4.3.2.
- Formerly EC 1.1.3.1.
|
| Cross-references |
|---|
| Biochemical Pathways; map number(s) | D6 ; E6 ; G6 ; D5 ; F6 |
| PROSITE | PDOC00482 |
| BRENDA | 1.1.3.15 |
| PUMA2 | 1.1.3.15 |
| PRIAM enzyme-specific profiles | 1.1.3.15 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.3.15 |
| IUBMB Enzyme Nomenclature | 1.1.3.15 |
| IntEnz | 1.1.3.15 |
| MEDLINE | Find literature relating to 1.1.3.15 |
| MetaCyc | 1.1.3.15 |
| UniProtKB/Swiss-Prot |
| Q9LRS0, GOX1_ARATH; | Q9LRR9, GOX2_ARATH; | P05414, GOX_SPIOL; |
| Q9UJM8, HAOX1_HUMAN; | Q9WU19, HAOX1_MOUSE; | Q3ZBW2, HAOX2_BOVIN; |
| Q9NYQ3, HAOX2_HUMAN; | Q9NYQ2, HAOX2_MOUSE; | Q07523, HAOX2_RAT; |
| Q54E41, HAOX_DICDI; |
|
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