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ENZYME

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NiceZyme View of ENZYME: EC 1.1.1.291

Official Name
2-hydroxymethylglutarate dehydrogenase.
Reaction catalysed
(S)-2-hydroxymethylglutarate + NAD(+) <=> 2-formylglutarate + NADH
Comment(s)
NADP(+) cannot replace NAD(+). Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri. Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1, EC 3.5.2.18, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.
Cross-references
BRENDA	1.1.1.291
PUMA2	1.1.1.291
PRIAM enzyme-specific profiles	1.1.1.291
KEGG Ligand Database for Enzyme Nomenclature	1.1.1.291
IUBMB Enzyme Nomenclature	1.1.1.291
IntEnz	1.1.1.291
MEDLINE	Find literature relating to 1.1.1.291
MetaCyc	1.1.1.291

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