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4th SIENA MEETING FROM GENOME TO PROTEOME:
Sept. 4-7, 2000, Siena, Italy
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SUNDAY
SEPTEMBER 3rd
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Registration
(Main
Auditorium, Via Laterina,8)
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Welcome
Party at San Francescos cloister
(sponsored by Large Scale Biology Corp.) |
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MONDAY
SEPTEMBER 4th
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Registration
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WELCOME
ADDRESS
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Prof.
P. Tosi (President of Siena University)
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Prof.
P. E. Valensin (Chief of Department.
of Molecular Biology)
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OPENING
REMARKS
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D.F.
Hochstrasser, J.-C. Sanchez, L. Bini, V. Pallini
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DECODING
THE HUMAN GENOME
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S.
Broder(Celera
Genomics, Rockville, MD, USA)
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KNOWLEDGE ACQUISITION |
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TOWARDS
A TOOLSET OF METHODS FOR COMPREHENSIVE PROTEOME ANALYSIS
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G.
L. Corthals, L. Tonella, S.G. Gygi, V.C. Wasinger,
D.F. Hochstrasser, R. Aebersold, J.-CSanchez(Sidney,
Australia; Geneva, Switzerland; Seattle, WA, USA))
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ADVANCES IN SAMPLE PREPARATION
FOR HIGH THROUGHPUT PROTEOMICS
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B.
Herbert, A. Castagna, J. Baker, P. G. Righetti,
K. Williams (Sydney,
Australia; Verona, Italy)
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COFFEE
BREAK
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LASER-CAPTURE
MICRODISSECTION AND PROTEOMICS-BASED APPROACHES IN CANCER RESEARCH
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R.E.
Banks, R Craven, P. Harnden, M. Rogers, P. Millner,
D. Pappin, P.J. Selby (Leeds,
London, UK)
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CHROMATOGRAPHY-BASED
PROTEOMIC ANALYSES: IDENTIFICATION AND QUALITATIVE COMPARISON
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S.
D. Patterson(Thousand
Oaks, CA, USA)
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RAPID
QUANTITATIVE MEASUREMENTS OF PROTEOMES
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R.
D. Smith, L. Pasa Tolic, M. S. Lipton, P. K. Jensen,
G. A. Anderson, T. D. Veenstra (Richland,
WA, USA)
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Polymer
MICRO-Chips for FAST Protein Analysis
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A.
Schwarz, F. Reymond, J. S. Rossier, M. Faupel, J. van Oostrum, H. H.
Girault (Lausanne,
Monthey, Basel, Switzerland)
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THE
SINGLE CELL PROTEOME PROJECT
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N.
J. Dovichi, Z. Zhang, S. Krylov, E. Arriaga, S.
Hu, D. Michels (Alberta,
Canada)
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LUNCH
(sponsored
by Amersham Pharmacia Biotech)
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IPG-DALT:
STATE OF THE ART
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A. Görg,
G. Boguth, A. Harder, C. Obermaier, B. Scheibe, R. Wildgruber, W. Weiss(Freising-Weihenstephan,
Germany)
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On
the adsorption of proteins to the bare silica wall and on the chemical
composition of the background electrolyte for minimizing it: a quantitative
study
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P.G.
Righetti, B. Verzola,
C. Gelfi (Verona,
Milan, Italy)
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CIPHERGENS
PROTEINCHIPÒ
SYSTEM: A NOVEL BENCHTOP PROTEOMICS PLATFORM FOR RAPID BIOMARKER DISCOVERY
AND VALIDATION
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H.
A. Davies, E. A. Dalmasso, B. Rich (Palo
Alto, CA, USA)
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REACTION
OF PROTEINS WITH FREE ACRYLAMIDE, N- SUBSTITUTED ACRYLAMIDES AND ACIDIC
AND BASIC IMMOBILINES AT ALKALINE pH VALUES AND ITS IMPLICATIONS IN PROTEOME
ANALYSIS
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M.
Hamdan, E. Bordini,
P.G. Righetti (Verona,
Italy)
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SILICON
MICROTECHNOLOGY FOR HIGH SENSITITVITY & HIGH SPEED AUTOMATED PROTEIN
IDENTIFICATION
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G.
Marko-Varga, S. Ekström, D. Ericsson,
J. Malmström, J. Nilsson, T Laurell(Lund,
Sweden)
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QUANTITATIVE
PROTEOMICS WITHOUT 2D GELS
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K.
Parker, Y. Huang, T. Nadler (Framingham,
MA, USA)
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STRATEGIES
FOR COMPREHENSIVE ANALYSES OF HUMAN PROTEOMES
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D.
W. Speicher, X. Zuo, K. D. Speicher, O. Kolbas,
P. Hembach, L. Echan (Philadelphia,
PA, USA)
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COFFEE
BREAK
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DEVELOPMENT
OF A HIGH DENSITY ADDRESSABLE PROTEIN ARRAY
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R.
W. Wagner(Lexington,
MA, USA)
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ADDING
VALUE TO GENOMES: DIRECT PROTEIN IDENTIFICATION
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IN
LARGE GENOMES BY MASS SPECTROMETRY
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B.
Kuster, P. Mortensen, J. Andersen, A. Podtelejnikov,
K. Budin, M. Mann
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(Odense,
Denmark)
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DIRECT
SOFTWARE INTERPRETATION OF DE NOVO SEQUENCE
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FROM
ESI-MS/MS DATA FOR NOVEL PROTEIN IDENTIFICATION
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USING
BLAST
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R.
Bordoli, J. Cottrell, E. Kapp, J. Langridge, R. Rachubinski, R.
Wozniak,
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J.
Smith, J. Skilling (Manchester,
Cambridge, UK; Edmonton, Canada)
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HIGH
RESOLUTION PROTEOME ANALYSIS BY FOURIER
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TRANSFORM-ICR-MASS
SPECTROMTRY: APPLICATIONS TO
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TARGET
ANTIGENS FOR AUTO-IMMUNE DISEASES FROM COMPLEX
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BIOLOGICAL
MIXTURES
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M.
Przybylski(Konstanz,
Germany)
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ANALYSIS
OF PROTEIN DIGESTS FROM 2D GELS USING A MALDI
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QIT
TOF MASS SPECTROMETER
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C.
Sutton, K. Tanaka, J. Yan, H. Montgomery, M. Dunn (Manchester,
Harefield, UK)
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EFFECT
OF ROSIGLITAZONE ON THE DIFFERENTIAL EXPRESSION
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OF
DIABETES AND OBESITY ASSOCIATED PROTEINS IN OB/OB
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MICE:
MOLECULAR TARGETS OF INSULIN SENSITIZATION AND
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ISLET
CELL DYSFUNCTION
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J.-C.
Sanchez, V. Rouge, G. Rosselat, M. Sennitt, D.
Chiappe, M. Heller,
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S.
Wang, A. Pallett, D. F. Hochstrasser, M. Cawthorne
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(Geneva,Switzerland;
Buckingham, UK)
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PROTEOMICS
OF RAT SERUM: INFLAMMATION AND
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ANTIINFLAMMATORY
DRUGS
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I.
Miller, I. Eberini, P. Villa, M. Fratelli, D.
Agnello, P. Ghezzi, L. Puglisi,
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M.
Gemeiner, C. R.Sirtori, E. Gianazza(Vienna,
Austria; Milano, Italy)
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CHANGES
IN HEPATIC PROTEIN LEVELS FOLLOWING TREATMENT
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WITH
ACETAMINOPHEN OR ITS NON-TOXIC REGIOISOMER 3-
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ACETAMIDOPHENOL
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M.
Fountoulakis, P. Berndt, U. A. Boelsterli, F.
Crameri, M. Winter,
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S.
Albertini, L. Suter (Basel,
Switzerland)
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PROTEOMIC
ANALYSIS OF JET FUEL TOXICITY
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F.
A. Witzmann (Columbus,
IN, USA)
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COFFEE
BREAK
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IDENTIFICATION
AND CHARACTERIZATION OF A NOVEL
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PROTEIN
INDUCED IN THE SYMPATHETIC NERVOUS SYSTEM
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FOLLOWING
GUANETHIDINE TREATMENT
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R.M.
Leimgruber, S.A. Aykent, N.R. Siegel, P.T. Manning (St.
Louis, MO, USA)
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PROTEOMICS
TO DISPLAY LOVASTATIN-INDUCED PROTEIN AND
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PATHWAY
REGULATION IN RAT LIVER
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S.
Steiner, C.L. Gatlin, J.J. Lennon, A.M. McGrath,
A.M. Aponte, A.J. Makusky,
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M.
C. Rohrs, N.L. Anderson (Rockville,
MD, USA)
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ARRAY-BASED
PROTEOMICS AND THE CHALLENGE OF HUMAN
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TISSUES
IN HEALTH AND DISEASE
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I.
Humphery-Smith(Utrecht,
The Netherlands)
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BIOSENSOR-BASED
APPLICATIONS FOR GPCR DEORPHANING
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C.
Williams, T. Addona, S. Cook, M. Knoppers, D.
Meyer. (Cambridge,
MA, USA)
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CHOIR
CONCERT (Chiesa di Santo Spirito, Piazza
S. Spirito)
(sponsored by Consorzio Siena Ricerche) |
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TUESDAY
SEPTEMBER 5th
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HOW PROTEINS SPEAK WITH ONE ANOTHER IN CELL |
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SIGNALING
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E.Fischer(Seattle,
USA)
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KNOWLEDGE ACQUISITION |
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2D
FLUORESCENT DIFFERENCE GEL ELECTROPHORESIS
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ADDRESSING
THE BOTTLENECKS IN 2D BASED PROTEOMICS
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APPROACHES
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C.
Story(UK)
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DETECTION
DOWN TO ONE MOLECULE
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D.
Twerenbold(Neuchâtel,
Switzerland)
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PROTEIN
DETECTION BY EXPONENTIAL AMPLIFICATION
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C.
R. Merril(Bethesda,
MD, USA)
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MPD
ENABLED ULTRA-SENSITIVE METHODS FOR PROTEOMICS
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A.
K. Drukier, P. Volkovitsky, I. R. Sagdeev, N.
Sirotina, P. Berndt,
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H.
Langen, J. Jacob, M. Cahill, A. Nordheim, R. Gregory, G. Miklos
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(Herndon
, Va., Kents, OH, USA; Basel, Switzerland; Tubingen, Germany; Sydney, Australia)
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COFFEE
BREAK
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QUANTITATIVE
PROTEOME ANALYSIS: METHODS AND
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APPLICATIONS
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S.
Gygi, B. Rist, T. Griffin, H. Zhao, R. Aebersold(Seattle,
WA, USA)
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QUANTITATION
AND DE NOVO SEQUENCING OF PROTEINS FROM
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1-
AND 2D GELS BY ISOTOPIC N-TERMINAL LABELLING
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M.
Quadroni, M. Münchbach, G. Miotto, P. James(Zürich,
Switzerland)
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MASS
SPECTROMETRY AND DATABASE INTERROGATION
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STRATEGIES
FOR GLOBAL PROTEIN IDENTIFICATION
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A.
L. Burlingame(San
Francisco, CA, USA)
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PROTEIN
IDENTIFICATION BASED ON MALDI-POST SOURCE
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DECAY
MS: NOT A BAD EXPERIENCE
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J.
Vandekerckhove, H. Demol, M. Puype, L. Martens,
R. Van Belleghem
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N. Berdenis, G. Thomas,K. Gevaert (Ghent,Brussels,
Belgium)
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IDENTIFICATION
OF PROTEINS CONTAINING
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POSTTRANSLATIONAL
MODIFICATIONS (PTMS) OR POINT
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MUTATIONS
BY MALDI-MS/-PSD
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H.
E. Meyer, K. Marcus, M. Blüggel, A. Sickmann (Bochum,
Germany)
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LUNCH(sponsored
by Applied Biosystems)
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A SOLUTION
FOR RAPID PROGRESS INPROTEOME PROJECTS
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B.
J. Walsh(Sydney, Australia)
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BENEFITS
OF FAST PROTEIN IDENTIFICATION FOR 3D-
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PROTEOMICS
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H.
Langen, P. Berndt (Basel,
Switzerland)
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COMPREHENSIVE
ONE STEP PROTEOME ANALYSIS BY THE
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MOLECULAR
SCANNER:QUANTITATIVE EVALUATION
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W.
V. Bienvenut, M. Heller, M. Müller, , S.
Paesano, V. Converset, R. Gras,
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P.-A.
Binz, J.-C. Sanchez, R.D. Appel, D. F. Hochstrasser (Geneva,
Switzerland)
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FUNCTIONAL
PROTEOMICS: FROM RECEPTOR TO SIGNAL
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CASCADE
TO GENE EXPRESSION
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J.
Godovac-Zimmermann(London,
UK)
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INVESTIGATING
THE MODULAR NATURE OF SIGNALING
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PATHWAYS
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P.
Hornbeck, J. Rush, H. Zhang (Beverly,
Massachusetts, USA)
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THE
NUTS AND BOLTS OF A MINIMALIST PROTEOMIC APPROACH.
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APPLICATION
TO THE INSULIN TRANSDUCTION PATHWAY IN
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THE
3T3-L1 ADIPOCYTE CELL LINE
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A.
Ducret, A. Kamassah, M. Chevallet, M. Gresser,
C. Ramachandran
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(Pointe-ClaireDorval,
Québec, Canada)
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COFFEE
BREAK
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UNRAVELING
TUMOR COMPLEXITY
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G.
Auer, A. Alaiya, U. Roblick, S. Huwendiek, A.
Hagman, B. Franzén,
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S.
Linder (Stockholm,
Sweden)
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PROTEOMIC
STRATEGIES IN BLADDER CANCER
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J.
E. Celis(Aarhus,
Denmark)
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MASS
SPECTROSCOPIC ANALYSIS OF GLIAL FIBRILLARY ACIDIC
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PROTEIN
AND ITS FRAGMENTS IN ASTROCYTOMA AND
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OLIGODENDROGLIOMA
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T.M.
Luider, P. Sillevis Smitt, M. Fountoulakis, J.
M. Kros
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(Rotterdam,
the Netherlands; Basel, Switzerland)
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STRATEGIES
TO STUDY MECHANISMS OF CHEMORESISTANCE IN
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CANCER
CELLS IN VITRO
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H.
Lage, S. Kohl, J. E. Celis, D. Schadendo |